The tissue-engineered vascular graft—past, present, and future

S Pashneh-Tala, S MacNeil… - Tissue Engineering Part B …, 2016 - liebertpub.com
Cardiovascular disease is the leading cause of death worldwide, with this trend predicted to
continue for the foreseeable future. Common disorders are associated with the stenosis or …

The therapeutic potential of the mesenchymal stem cell secretome in ischaemic stroke

CJ Cunningham, E Redondo-Castro… - Journal of Cerebral …, 2018 - journals.sagepub.com
Mesenchymal stem cells (MSCs) hold great potential as a regenerative therapy for stroke,
leading to increased repair and functional recovery in animal models of cerebral ischaemia …

Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial

DC Hess, LR Wechsler, WM Clark, SI Savitz… - The Lancet …, 2017 - thelancet.com
Background Multipotent adult progenitor cells are a bone marrow-derived, allogeneic, cell
therapy product that modulates the immune system, and represents a promising therapy for …

Use of mesenchymal stem cells for therapy of cardiac disease

V Karantalis, JM Hare - Circulation research, 2015 - Am Heart Assoc
Despite substantial clinical advances over the past 65 years, cardiovascular disease
remains the leading cause of death in America. The past 15 years has witnessed major …

Same or not the same? Comparison of adipose tissue-derived versus bone marrow-derived mesenchymal stem and stromal cells

M Strioga, S Viswanathan, A Darinskas… - Stem cells and …, 2012 - liebertpub.com
Mesenchymal stem/stromal cells (MSCs) comprise a heterogeneous population of cells with
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …

Articular cartilage: from formation to tissue engineering

S Camarero-Espinosa, B Rothen-Rutishauser… - Biomaterials …, 2016 - pubs.rsc.org
Hyaline cartilage is the nonlinear, inhomogeneous, anisotropic, poro-viscoelastic connective
tissue that serves as friction-reducing and load-bearing cushion in synovial joints and is vital …

Mesenchymal stromal cells and cutaneous wound healing: a comprehensive review of the background, role, and therapeutic potential

MS Hu, MR Borrelli, HP Lorenz… - Stem cells …, 2018 - Wiley Online Library
Cutaneous wound repair is a highly coordinated cascade of cellular responses to injury
which restores the epidermal integrity and its barrier functions. Even under optimal healing …

A perivascular origin for mesenchymal stem cells in multiple human organs

M Crisan, S Yap, L Casteilla, CW Chen, M Corselli… - Cell stem cell, 2008 - cell.com
Mesenchymal stem cells (MSCs), the archetypal multipotent progenitor cells derived in
cultures of developed organs, are of unknown identity and native distribution. We have …

Molecular regulation of vessel maturation

RK Jain - Nature medicine, 2003 - nature.com
The maturation of nascent vasculature, formed by vasculogenesis or angiogenesis, requires
recruitment of mural cells, generation of an extracellular matrix and specialization of the …

[HTML][HTML] Mesenchymal stem cells: revisiting history, concepts, and assays

P Bianco, PG Robey, PJ Simmons - Cell stem cell, 2008 - cell.com
The concept of mesenchymal stem cells has gained wide popularity. Despite the rapid
growth of the field, uncertainties remain with respect to the defining characteristics of these …