Macrolides are a diverse class of hydrophobic compounds characterized by a macrocyclic
lactone ring and distinguished by variable side chains/groups. Some of the most well …

Proteins targeted to the secretory pathway start their intracellular journey by being
transported across biological membranes such as the endoplasmic reticulum (ER). A central …

Mycobacterium ulcerans causes Buruli Ulcer, a neglected infectious skin disease that
typically progresses from an early non-ulcerative lesion to an ulcer with undermined edges …

Multiple myeloma (MM) is an incurable malignancy characterized by the uncontrolled
expansion of plasma cells in the bone marrow. While proteasome inhibitors like bortezomib …

Mycolactone is a cytotoxic lipid metabolite produced by Mycobacterium ulcerans, the
environmental pathogen responsible for Buruli ulcer, a neglected tropical disease …

Mycobacterial pathogens can be categorized into three broad groups: Mycobacterium
tuberculosis complex causing tuberculosis, M. leprae and M. lepromatosis causing leprosy …

Mycobacterium ulcerans causes Buruli ulcer, a neglected tropical skin disease manifesting
as chronic wounds that can leave victims with major, life‐long deformity and disability …

In the recent decade, scientific communities have toiled to tackle the emerging burden of
drug-resistant tuberculosis (DR-TB) and rapidly growing opportunistic nontuberculous …

Buruli ulcer (BU) is a neglected, tropical infectious disease of the skin and the subcutaneous
tissue caused by Mycobacterium ulcerans. This pathogen has emerged as a new species …

Mycobacterium ulcerans is a human pathogen that causes a necrotizing skin disease known
as Buruli ulcer. Necrosis of infected skin is driven by bacterial production of mycolactone, a …