Early repositioning through compound set enrichment analysis: a knowledge-recycling strategy
Despite famous serendipitous drug repositioning success stories, systematic projects have
not yet delivered the expected results. However, repositioning technologies are gaining …
not yet delivered the expected results. However, repositioning technologies are gaining …
Building Graphs To Describe Dynamics, Kinetics, and Energetics in the d-ALa:d-Lac Ligase VanA
The d-Ala: d-Lac ligase, VanA, plays a critical role in the resistance of vancomycin. Indeed, it
is involved in the synthesis of a peptidoglycan precursor, to which vancomycin cannot bind …
is involved in the synthesis of a peptidoglycan precursor, to which vancomycin cannot bind …
Pathogenicity phenomena in three model systems: from network mining to emerging system-level properties
NC Santos, MO Pereira, A Lourenco - Briefings in Bioinformatics, 2015 - academic.oup.com
Understanding the interconnections of microbial pathogenicity phenomena, such as biofilm
formation, quorum sensing and antimicrobial resistance, is a tremendous open challenge for …
formation, quorum sensing and antimicrobial resistance, is a tremendous open challenge for …
Mechanism-driven hypothesis generation support for a predictive adverse effect in colorectal cancer treatment
S Schaaf - 2019 - edoc.ub.uni-muenchen.de
This bioinformatics thesis describes work and results from a study on a use case in the
context of colorectal cancer. Background of the studies is an observation form the clinical …
context of colorectal cancer. Background of the studies is an observation form the clinical …
[PDF][PDF] Hatóanyagok és terápiás célpontok vizsgálata adatmérnöki eszközökkel
TG Botond - core.ac.uk
Az új évezred valóban egy új korszakot is nyitott számos tudományos, technológiai és
gazdasági területen. A nyugati társadalmak öregedésének egészségügyi kiadásai évtizedek …
gazdasági területen. A nyugati társadalmak öregedésének egészségügyi kiadásai évtizedek …
[PDF][PDF] Hatóanyagok és terápiás célpontok vizsgálata adatmérnöki eszközökkel
G Temesi - 2015 - repo.lib.semmelweis.hu
Az új évezred valóban egy új korszakot is nyitott számos tudományos, technológiai és
gazdasági területen. A nyugati társadalmak öregedésének egészségügyi kiadásai évtizedek …
gazdasági területen. A nyugati társadalmak öregedésének egészségügyi kiadásai évtizedek …
[PDF][PDF] Integrative Systems Approaches Towards Brain Pharmacology and Polypharmacology
M Shahid - 2014 - core.ac.uk
Polypharmacology is considered as the future of drug discovery and emerges as the next
paradigm of drug discovery. The traditional drug design is primarily based on a” one target …
paradigm of drug discovery. The traditional drug design is primarily based on a” one target …
Mining quorum sensing in pathogenic P. aeruginosa and C. albicans
NC Santos - 2013 - search.proquest.com
O estudo do fenómeno de cross-talking entre P. aeruginosa e C. albicans tem sido focado
essencialmente nos processos de quorum sensing e formação de biofilmes, identificando …
essencialmente nos processos de quorum sensing e formação de biofilmes, identificando …