Colon cancer affects both men and women and is the world's second most significant cause
of cancer-related mortality. Colon cancer death rates have risen worldwide due to the …

The mammalian or mechanistic target of rapamycin (mTOR) pathway plays a crucial role in
regulation of cell survival, metabolism, growth and protein synthesis in response to upstream …

Abstract Ethnopharmacological relevance Sijunzi Decoction (SJZD), as a famous classical
prescription for the treatment of colorectal cancer (CRC) in the traditional Chinese medicine …

Abstract Background Circular RNAs (circRNAs), important members of the noncoding RNA
family, have been recently revealed to play a role in the pathogenic progression of diseases …

Background Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …

Colorectal cancer (CRC) is one of the most common types of cancers in humans and is
closely linked to the global cancer-related mortalities worldwide. Molecular pathological …

Colorectal‐cancer (CRC) is the third leading cause of death due to cancer, supporting the
need for identification of novel anticancer drug to improve the efficacy of current‐therapy …

Abstract Poly-ADP-ribose polymerase 1 (PARP-1) and PARP-2 are DNA damage sensors
that are most active during S-phase of the cell cycle and that have wider-reaching roles in …

Simple Summary To improve efficacy of solid cancer treatment, efforts have shifted towards
targeting both the cancer cells and the surrounding tumour tissue they grow in. The lysyl …

Radiotherapeutic resistance is a major obstacle for the effective treatment of colorectal
cancer (CRC). MicroRNAs (miRNAs) play a critical role in chemoresistance and …