Osteoporosis is a complex human disease that results in increased susceptibility to fragility
fractures. It can be phenotypically characterized using several traits, including bone mineral …

Background Many studies have reported associations between estrogen receptor (ER) gene
polymorphisms and postmenopausal osteoporosis (PMOP) risk and bone mineral density …

Estrogen plays a role in breast cancer development, and genetic polymorphisms in estrogen
receptor gene ER-α and genes regulating estrogen biosynthesis and metabolisms are …

Dental fluorosis (DF) is one of the important performances of endemic fluorosis. Some
studies indicated that estrogen receptor (ESR) gene polymorphisms were associated with …

Osteoporosis (OP) is a common skeletal disorder characterized by low bone mineral density
(BMD) and is a common health problem in Mexico. To date, few genes affecting BMD …

Objective: The study aimed to explore the associations of rs4988300 and rs634008 in the
low-density lipoprotein receptor–related protein 5 (LRP5) gene with bone mineral density …

To further elucidate the processes involved in the physiology of bone-protection by
estrogens, ovariectomized (OVX) rats were treated subcutaneously with 17β-estradiol (E2) …

Background: Recently, the roles of ESR1 and ESR2 polymorphisms in osteoporosis have
been extensively reported, with conflicting findings. Therefore, we performed this present …

Estrogen regulates bone homeostasis and has a cardio-protective effect. Its physiological
functions are mediated through receptors (ER) whose expression can be regulated by …

The Sp1 binding site polymorphism in collagen type I alpha 1 gene (COLIA1) has been
associated with osteoporosis (OP) and bone mineral density (BMD). The aim of this study …