Inflammatory bowel disease (IBD)—consisting of ulcerative colitis and Crohn's disease—is a
complex, heterogeneous, immune-mediated inflammatory condition with a multifactorial …

Summary Background 5‐aminosalicylates (5‐ASA) are widely used in Crohn's disease (CD)
despite guidelines advising otherwise. We aimed to assess in nationwide study the …

Background & Aims In this nationwide study from the Israeli Inflammatory Bowel Disease
Research Nucleus, we aimed to describe the incidence of very early onset inflammatory …

Background and aims Perianal fistulizing Crohn's disease (PFCD)-associated anorectal and
fistula cancers are rare but often devastating diagnoses. However, given the low incidence …

Background Surgical management of anal fistulas in Crohn's disease (CD) is associated
with high failure rates, and treatment options are limited due to ongoing proctitis, multiple …

Background In this nationwide study we aimed to compare the durability of the first initiated
biologic in Crohn's disease [CD], stratified by monotherapy and combotherapy. Methods We …

Abstract Background Fistulizing perianal Crohn's disease (CD) is a debilitating condition
associated with significant morbidity and reduction in the quality of life. Magnetic resonance …

Background Since data on predictors of complicated Crohn's disease (CD) from unselected
populations are scarce, we aimed to utilize a large nationwide cohort, the epi-IIRN, to …

Methods: We included all patients with newly diagnosed CD from 2005 to 2019 at two Israeli
Health Maintenance Organizations, covering 78% of the population. A combination of ICD-9 …

Background Patients with inflammatory bowel disease are at increased risk of colorectal and
extra‐intestinal cancer. However, the overall cancer risk in patients with Crohn's disease …