Recent advances in the synthesis of biologically active cinnoline, phthalazine and quinoxaline derivatives
In the recent decades, N-heterocycles are widely used as versatile scaffolds for the
development of biologically active compounds and considered as one of the privileged …
development of biologically active compounds and considered as one of the privileged …
[PDF][PDF] A valuable insight into recent advances on antimicrobial activity of piperazine derivatives
The worldwide problem of microbial resistance has drawn utmost attention for medicinal
chemists because of failure of currently available antimicrobial therapy against microbial …
chemists because of failure of currently available antimicrobial therapy against microbial …
[HTML][HTML] Cinnoline scaffold—a molecular heart of medicinal chemistry?
M Szumilak, A Stanczak - Molecules, 2019 - mdpi.com
The cinnoline nucleus is a very important bicyclic heterocycle that is used as the structural
subunit of many compounds with interesting pharmaceutical properties. Cinnoline …
subunit of many compounds with interesting pharmaceutical properties. Cinnoline …
[HTML][HTML] Understanding the aqueous chemistry of quinoline and the diazanaphthalenes: insight from DFT study
The inter-fragment interactions at various binding sites and the overall cluster stability of
quinolone (QNOL), cinnoline (CNOL), quinazoline (QNAZ), and quinoxaline (QNOX) …
quinolone (QNOL), cinnoline (CNOL), quinazoline (QNAZ), and quinoxaline (QNOX) …
Synthesis and evaluation of anti-inflammatory activity of some cinnoline derivatives-4 (-2-amino-thiophene) cinnoline-3-carboxamide
A prolonged increase in pro-inflammatory cytokines, TNF-α and IL-6 occurs in inflammatory
diseases. Although cinnoline belongs to a family of fairly well known heterocycles, the …
diseases. Although cinnoline belongs to a family of fairly well known heterocycles, the …
Synthesis and biological activity of novel amidrazones incorporating 5-nitroimidazole, ciprofloxacin, and 7-chloro-4-piperazinylquinoline
Abstract Series of new amidrazones Ia–c, IIa–c, and IIIc, incorporating 5-nitroimidazole (a),
ciprofloxacin (b), and 7-chloro-4-piperazinylquinoline (c) moieties, were synthesized by …
ciprofloxacin (b), and 7-chloro-4-piperazinylquinoline (c) moieties, were synthesized by …
[HTML][HTML] Synthesis and Properties of 6-Aryl-4-azidocinnolines and 6-Aryl-4-(1,2,3-1H-triazol-1-yl)cinnolines
NA Danilkina, NS Bukhtiiarova, AI Govdi, AA Vasileva… - Molecules, 2019 - mdpi.com
An efficient approach towards the synthesis of 6-aryl-4-azidocinnolines was developed with
the aim of exploring the photophysical properties of 6-aryl-4-azidocinnolines and their click …
the aim of exploring the photophysical properties of 6-aryl-4-azidocinnolines and their click …
Tuning the Stability and the Reactivity of Substituted [3] Dendralenes for Quick Access to Diverse Copiously Functionalized Fused Polycycles with Step and Atom …
This is the first comprehensive study that details the synthesis of stable acyclic trisubstituted
[3] dendralenes and deciphers their structural requisite for a successful diene transmissive …
[3] dendralenes and deciphers their structural requisite for a successful diene transmissive …
Synthesis and in vitro anti microbial evaluation including anti-malarial activity of pyrazole based novel cinnoline derivatives
SH Unnissa, N Nisha, GK Reddy - Journal of Applied …, 2015 - japsonline.com
Abstract A Series of 4-methyl-3-[5-(substituted phenyl)-4, 5-dihydro-1H-Pyrazol-3-yl]
Cinnoline-6-Sulfonamide were synthesized from 4-methyl-3-acetylcinnoline-6-Sulfonamido …
Cinnoline-6-Sulfonamide were synthesized from 4-methyl-3-acetylcinnoline-6-Sulfonamido …
[HTML][HTML] Synthesis and antibacterial activity of N1-(carbazol-3-yl)amidrazones incorporating piperazines and related congeners
A selected set of N 1-(4-chloro-9-ethylcarbazol-3-yl) amidrazones (7a–n) has been
synthesized by reacting the respective hydrazonoyl chloride 5 derived from 3-amino-9 …
synthesized by reacting the respective hydrazonoyl chloride 5 derived from 3-amino-9 …