Fluorescence correlation spectroscopy (FCS) is a powerful technique for quantification of
molecular dynamics, and it has been widely applied in diverse fields, eg, biomedicine …

We review the emerging method of super-resolved cryogenic correlative light and electron
microscopy (srCryoCLEM). Super-resolution (SR) fluorescence microscopy and cryogenic …

Prion-like RNA binding proteins (RBPs) such as TDP43 and FUS are largely soluble in the
nucleus but form solid pathological aggregates when mislocalized to the cytoplasm. What …

To study charge-dependent interactions of nanoparticles (NPs) with biological media and
NP uptake by cells, colloidal gold nanoparticles were modified with amphiphilic polymers to …

Recent studies have firmly established that cellular uptake of nanoparticles is strongly
affected by the presence and the physicochemical properties of a protein adsorption layer …

The dimensions of unfolded and intrinsically disordered proteins are highly dependent on
their amino acid composition and solution conditions, especially salt and denaturant …

In order to evaluate the risk of engineered nanomaterials in the natural environment, one
must determine their mobility, among other factors. Such determinations are difficult given …

Assembly of highly curved membrane structures is essential to cellular physiology. The
prevailing view has been that proteins with curvature-promoting structural motifs, such as …

Doping of carbon nanoparticles with impurity atoms is central to their application,. However,
doping has proven elusive for very small carbon nanoparticles because of their limited …

The GroEL/ES chaperonin system functions as a protein folding cage. Many obligate
substrates of GroEL share the (βα) 8 TIM-barrel fold, but how the chaperonin promotes …