Background: The field of bile acid research has become tremendously active. Bile acids
have been shown to act as signaling molecules that are involved in many metabolic …

Following the drug administration, patients are exposed not only to the parent drug itself, but
also to the metabolites generated by drug-metabolizing enzymes. The role of drug …

This study aims to investigate the impact of ACE (rs4343) and AT1R (rs 5182) genetic
polymorphisms on the outcome of acute coronary syndrome (ACS) in patients on captopril …

The perception of the impact of precision and personalized medicine is easy for monogenic
(both single-disease gene and genetically heterogeneous diseases) and monofactorial …

Introduction: Even if cardiovascular disease (CVD) drugs are supported by high level proofs,
the results of CVD treatment present great disparities: there are still patients dying with …

Introduction. Prosthetic valve thrombosis is usually a subacute or chronic condition, although
it may also present with a fresh thrombus. It occurs in two forms: obstructive and non …

With the completion of human sequencing and availability of new biotechnology tools,
molecular characterization of diseases at individual level is feasible and sustainable. In this …

Introduction. Prosthetic valve thrombosis is usually a subacute or chronic condition, although
it may also present with a fresh thrombus. It occurs in two forms: obstructive and non …