Recent miRNA research in asthma

R Sharma, A Tiwari, MJ McGeachie - Current allergy and asthma reports, 2022 - Springer
Abstract Purpose of Review The study of microRNA in asthma has revealed a vibrant new
level of gene regulation underlying asthma pathology. Several miRNAs have been shown to …

Nerve growth factor: A potential therapeutic target for lung diseases

P Liu, S Li, L Tang - International Journal of Molecular Sciences, 2021 - mdpi.com
The lungs play a very important role in the human respiratory system. However, many factors
can destroy the structure of the lung, causing several lung diseases and, often, serious …

The PPARα and PPARγ epigenetic landscape in cancer and immune and metabolic disorders

J Porcuna, J Mínguez-Martínez, M Ricote - International journal of …, 2021 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) are ligand-modulated nuclear
receptors that play pivotal roles in nutrient sensing, metabolism, and lipid-related processes …

PPARG: a promising therapeutic target in breast cancer and regulation by natural drugs

DH Li, XK Liu, XT Tian, F Liu, XJ Yao… - PPAR research, 2023 - Wiley Online Library
Breast cancer (BC) is the most common type of cancer among females. Peroxisome
proliferator‐activated receptor gamma (PPARG) can regulate the production of adipocyte …

[HTML][HTML] The role of microRNAs in nicotine signaling

K Hajiasgharzadeh, B Naghipour, P Shahabi… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Cigarette smoking is a harmful habit that is widespread around the world. It is among the
well-known lifestyle-related risk factors for many diseases. Nicotine, as its principal …

Cucurbitacin E ameliorates airway remodelling by inhibiting nerve growth factor expression in nicotine‐treated bronchial epithelial cells and mice: The key role of let …

H Liu, L Yu, B Shao, N Yin, L Li… - Basic & Clinical …, 2022 - Wiley Online Library
Cucurbitacin E (CuE) shows potential to handle airway remodelling. In the current study, the
effects of CuE on nicotine‐induced airway remodelling were explored by focussing on its …

Nerve growth factor monoclonal antibody Tanezumab alleviates Kashin-Beck Disease Rat pain by impacting DRG signal transduction

W Haifan, H Yigeng, Y Weiming, Z Qinfeng, L Sen… - 2023 - researchsquare.com
Method After the establishment of KBD models in SD rats, the rats were injected with the
NGF monoclonal antibody Tanezumab (Tnz) at doses of 2.5 and 5.0 mg/kg every week …