Proteogenomic data and resources for pan-cancer analysis

Y Li, Y Dou, FDV Leprevost, Y Geffen, AP Calinawan… - Cancer cell, 2023 - cell.com
Summary The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium
(CPTAC) investigates tumors from a proteogenomic perspective, creating rich multi-omics …

Enrichment driven glycoproteomics: New materials, new methods, and beyond

Y Xiong, M Li, Y Liu, X Liang, G Qing - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Glycoproteomics is a rapidly growing field that aims to identify and characterize protein
glycosylation events at a system level. However, the analysis of protein glycosylation in …

[HTML][HTML] Application of nanomaterials in proteomics-driven precision medicine

Y Zhang, H Yang, Y Yu, Y Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
Nanostructured devices and nanoparticles have fundamentally reshaped the development
of precision healthcare in recent decades. Meanwhile, mass spectrometry (MS)-based …

Data-independent acquisition-based mass spectrometry (DIA-MS) for quantitative analysis of intact N-linked glycopeptides

M Dong, TSM Lih, M Ao, Y Hu, SY Chen… - Analytical …, 2021 - ACS Publications
N-linked protein glycosylation is a key regulator in various biological functions. Previous
studies have shown that aberrant glycosylation is associated with many diseases. Therefore …

Dendrimer-assisted boronate affinity cellulose foams for the efficient and selective separation of glycoproteins

X Yao, S Zhang, L Qian, M Du - Carbohydrate Polymers, 2021 - Elsevier
Surfaces engineered to identify and enrich glycoproteins are of considerable interest in the
diagnostic and detection fields. A boronate affinity (BA) material was proposed as a potential …

On the road to accurate protein biomarkers in prostate cancer diagnosis and prognosis: current status and future advances

Y Yan, SY Yeon, C Qian, S You, W Yang - International Journal of …, 2021 - mdpi.com
Prostate cancer (PC) is a leading cause of morbidity and mortality among men worldwide.
Molecular biomarkers work in conjunction with existing clinicopathologic tools to help …

Novel serum proteomic biomarkers for early diagnosis and aggressive grade identification of prostate cancer

C Wang, G Liu, Y Liu, Z Yang, W Xin, M Wang… - Frontiers in …, 2022 - frontiersin.org
Background Prostate cancer (PCa) is one of the most common tumors and the second
leading cause of cancer-related death in men. The discovery of novel biomarkers for PCa …

Biomarkers for the Detection and Risk Stratification of Aggressive Prostate Cancer

S Eickelschulte, AL Riediger, AK Angeles, F Janke… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer is a heterogeneous disease and a major cause of cancer
deaths worldwide. The most widely used prostate cancer biomarker, prostate-specific …

Development of a predictive model to distinguish prostate cancer from benign prostatic hyperplasia by integrating serum glycoproteomics and clinical variables

C Gabriele, F Aracri, LE Prestagiacomo, MA Rota… - Clinical Proteomics, 2023 - Springer
Abstract Background Prostate Cancer (PCa) represents the second leading cause of cancer-
related death in men. Prostate-specific antigen (PSA) serum testing, currently used for PCa …

Alterations in protein expression and site-specific N-glycosylation of prostate cancer tissues

S Sugár, G Tóth, F Bugyi, K Vékey, K Karászi… - Scientific reports, 2021 - nature.com
Identifying molecular alterations occurring during cancer progression is essential for a
deeper understanding of the underlying biological processes. Here we have analyzed …