Viroplasms are cytoplasmic, membraneless structures assembled in rotavirus (RV)-infected
cells, which are intricately involved in viral replication. Two virus-encoded, non-structural …

Casein kinase 1α (CK1α) is a multifunctional protein belonging to the CK1 protein family that
is conserved in eukaryotes from yeast to humans. It regulates signaling pathways related to …

The replication of rotavirus is a complex process that is orchestrated by an exquisite
interplay between the rotavirus non-structural and structural proteins. Subsequent to particle …

Many viruses sequester the materials needed for their replication into discrete subcellular
factories. For rotaviruses (RVs), these factories are called viroplasms, and they are formed in …

Rotaviruses, the major causative agents of infantile diarrhea worldwide, are, in general,
highly species-specific. Interspecies virus transmission is thought to be one of the important …

Cell-to-cell communication in plants involves the trafficking of macromolecules through
specialized intercellular organelles, termed plasmodesmata. This exchange of proteins and …

The rotaviruses, members of the family Reoviridae, are icosahedral triple-layered viruses
with genomes consisting of 11 segments of double-stranded (ds) RNA. A characteristic …

Avian rotaviruses are broadly distributed among birds, but only scarcely characterized on
the molecular level. The VP4-, VP6-, VP7-and NSP5-encoding sequences of eight group A …

For many medically relevant viruses, there is now considerable evidence that both viral and
cellular kinases play important roles in viral infection. Ultimately, these kinases, and the …

Rotavirus (RV) replicates in round-shaped cytoplasmic viral factories, although how they
assemble remains unknown. During RV infection, NSP5 undergoes hyperphosphorylation …