Photoreceptor cells and RPE contribute to the development of diabetic retinopathy

D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …

The electroretinogram in diabetic retinopathy

R Tzekov, GB Arden - Survey of ophthalmology, 1999 - Elsevier
Electroretinography (ERG) is an objective method of evaluating retinal function. Since its
introduction to clinical practice in the 1940s, it has become a useful and routine diagnostic …

Choriocapillaris degeneration and related pathologic changes in human diabetic eyes

J Cao, DS McLeod, CA Merges… - Archives of …, 1998 - jamanetwork.com
Objectives To measure the extent of choriocapillaris degeneration (CCD) in diabetic
choroids and to study the association of CCD with choroidal neovascularization and …

Early retinal neurovascular impairment in patients with diabetes without clinically detectable retinopathy

Y Zeng, D Cao, H Yu, D Yang, X Zhuang… - British Journal of …, 2019 - bjo.bmj.com
Aims To investigate the function and the corresponding neurovascular structures in patients
with diabetes without clinically detectable retinopathy. Methods Sixty-six patients with type 2 …

Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina

SH Park, JW Park, SJ Park, KY Kim, JW Chung… - Diabetologia, 2003 - Springer
Aims/hypothesis Neurodegenerative changes in the diabetic retina occurring before diabetic
retinopathy could be inevitable by the altered energy (glucose) metabolism, in the sense that …

[HTML][HTML] Multifocal electroretinogram delays reveal local retinal dysfunction in early diabetic retinopathy

B Fortune, ME Schneck… - … ophthalmology & visual …, 1999 - tvst.arvojournals.org
purpose. To identify local retinal abnormalities in diabetic patients with and without
retinopathy, by using the multifocal electroretinogram (M-ERG). methods. Electroretinograms …

[HTML][HTML] Neurodegeneration in diabetic retinopathy: potential for novel therapies

AJ Barber, B Baccouche - Vision research, 2017 - Elsevier
The complex pathology of diabetic retinopathy (DR) affects both vascular and neural tissue.
The characteristics of neurodegeneration are well-described in animal models but have …

Neuronal and glial cell abnormality as predictors of progression of diabetic retinopathy

EL Fletcher, JA Phipps, MM Ward… - Current …, 2007 - ingentaconnect.com
Diabetes is known to cause significant alterations in the retinal vasculature. Indeed, diabetic
retinopathy is the leading cause of blindness in those of working age. Considerable …

Clinical electroretinography in diabetic retinopathy: A review

JJ McAnany, OS Persidina, JC Park - Survey of ophthalmology, 2022 - Elsevier
The electroretinogram (ERG) is a noninvasive, objective technique to evaluate retinal
function that has become increasingly important in the study of diabetic retinopathy. We …

Photoreceptors in diabetic retinopathy

TS Kern, BA Berkowitz - Journal of diabetes investigation, 2015 - Wiley Online Library
Although photoreceptors account for most of the mass and metabolic activity of the retina,
their role in the pathogenesis of diabetic retinopathy has been largely overlooked. Recent …