Therapeutic implications of caffeic acid in cancer and neurological diseases

M Alam, S Ahmed, AM Elasbali, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA
and its derivatives have been used for many centuries due to their natural healing and …

Phenylpropanoids and its derivatives: biological activities and its role in food, pharmaceutical and cosmetic industries

Neelam, A Khatkar, KK Sharma - Critical Reviews in Food Science …, 2020 - Taylor & Francis
Phenylpropanoids and their derivatives are plant secondary metabolites widely present in
fruits, vegetables, cereal grains, beverages, spices and herbs. They are known to have …

Hybrid molecules based on caffeic acid as potential therapeutics: A focused review

X Zhao, Z Liu, H Liu, J Guo, S Long - European Journal of Medicinal …, 2022 - Elsevier
Caffeic acid-based compounds possess a high degree of structural diversity and show a
variety of pharmacological properties, providing a useful framework for the discovery of new …

Caffeic acid phenethyl ester (CAPE): biosynthesis, derivatives and formulations with neuroprotective activities

R Pérez, V Burgos, V Marín, A Camins, J Olloquequi… - Antioxidants, 2023 - mdpi.com
Neurodegenerative disorders are characterized by a progressive process of degeneration
and neuronal death, where oxidative stress and neuroinflammation are key factors that …

Metal chelation therapy and Parkinson's disease: A critical review on the thermodynamics of complex formation between relevant metal ions and promising or …

M Tosato, V Di Marco - Biomolecules, 2019 - mdpi.com
The present review reports a list of approximately 800 compounds which have been used,
tested or proposed for Parkinson's disease (PD) therapy in the year range 2014–2019 …

Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells

Y Okada, M Okada - Molecular Biology Reports, 2020 - Springer
The circadian timing system of mammals is synchronized in concert with a central clock, but
is also influenced by additional stimuli, including nutrients. However, little research has been …

Qualitative Phytochemical Fingerprint and Network Pharmacology Investigation of Achyranthes aspera Linn. Extracts

KI Sinan, G Zengin, D Zheleva-Dimitrova, OK Etienne… - Molecules, 2020 - mdpi.com
Achyranthes aspera Linn.(Amaranthaceae), commonly known as the Prickly Chaff flower, is
used as herbal medicine in the Ivorian's culture, Africa. Nonetheless, there is currently a …

[HTML][HTML] Role of CAPE in reducing oxidative stress in animal models with traumatic brain injury

RA Nasution, AA Islam, M Hatta, A Turchan… - Annals of Medicine and …, 2020 - Elsevier
Introduction The central nervous system (CNS) is the most metabolically active organ
characterized by high oxygen demand and relatively low anti-oxidative activity, which makes …

Huperzia serrata Extract 'NSP01' With Neuroprotective Effects-Potential Synergies of Huperzine A and Polyphenols

N Callizot, ML Campanari, L Rouvière… - Frontiers in …, 2021 - frontiersin.org
Huperzia serrata (Thunb.) Trevis is widely used in traditional asiatic medicine to treat many
central disorders including, schizophrenia, cognitive dysfunction, and dementia. The major …

An outlook on the role of decaffeinated coffee in neurodegenerative diseases

R Colombo, A Papetti - Critical Reviews in Food Science and …, 2020 - Taylor & Francis
Coffee is reported to be among the most widely consumed beverages in the world and
coffee consumption has been associated with reductions in the risk of several chronic …