[HTML][HTML] Flavonoids are promising safe therapy against COVID-19

MM Alzaabi, R Hamdy, NS Ashmawy… - Phytochemistry …, 2022 - Springer
Flavonoids are a class of phenolic natural products, well-identified in traditional and modern
medicines in the treatment of several diseases including viral infection. Flavonoids showed …

Luteolin as a modulator of skin aging and inflammation

F Gendrisch, PR Esser, CM Schempp, U Wölfle - Biofactors, 2021 - Wiley Online Library
Luteolin belongs to the group of flavonoids and can be found in flowers, herbs, vegetables
and spices. It plays an important role in defending plants, for example against UV radiation …

[HTML][HTML] ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment

C Tan, H Fan, J Ding, C Han, Y Guan, F Zhu, H Wu… - Materials Today Bio, 2022 - Elsevier
Oxidative stress, caused by excessive production of reactive oxygen species (ROS), plays a
crucial role in the occurrence and development of ulcerative colitis (UC). We developed …

Luteolin inhibits autophagy in allergic asthma by activating PI3K/Akt/mTOR signaling and inhibiting Beclin-1-PI3KC3 complex

S Wang, T Wuniqiemu, W Tang, F Teng, Q Bian… - International …, 2021 - Elsevier
Allergic asthma is a common chronic inflammatory disease characterized by airway
inflammation, mucus hypersecretion and airway remodeling. Autophagy is a highly …

An insight into the roles of dietary tryptophan and its metabolites in intestinal inflammation and inflammatory bowel disease

X Li, ZH Zhang, HM Zabed, J Yun… - Molecular Nutrition & …, 2021 - Wiley Online Library
Inflammatory bowel disease (IBD) is complex, chronic, and relapsing gastrointestinal
inflammatory disorders, which includes mainly two conditions, namely ulcerative colitis (UC) …

Luteolin activates Tregs to promote IL-10 expression and alleviating caspase-11-dependent pyroptosis in sepsis-induced lung injury

Z Zhang, DY Zhang, K Xie, CJ Wang, F Xu - International …, 2021 - Elsevier
Objectives Acute respiratory distress syndrome (ARDS) is characterized by an excessive
pulmonary inflammatory response. Pyroptosis is a newly form of programmed inflammatory …

[HTML][HTML] Immunopharmacological activities of luteolin in chronic diseases

L Huang, MY Kim, JY Cho - International Journal of Molecular Sciences, 2023 - mdpi.com
Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits
(eg, anti-inflammatory and anti-tumor functions). Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) …

Effects of flavonoids and its derivatives on immune cell responses

G Martínez, MR Mijares… - Recent Patents on …, 2019 - ingentaconnect.com
Background: Various pieces of evidence have shown that people who consume foods rich in
polyphenolic and flavonoids compounds have a lower incidence of inflammatory …

Luteolin regulates the differentiation of regulatory T cells and activates IL‐10‐dependent macrophage polarization against acute lung injury

K Xie, Y Chai, S Lin, F Xu… - Journal of immunology …, 2021 - Wiley Online Library
Objectives. Inflammatory disease characterized by clinical destructive respiratory disorder is
called acute lung injury/acute respiratory distress syndrome (ALI/ARDS). Studies have …

[HTML][HTML] Active ingredients from Chinese medicine plants as therapeutic strategies for asthma: Overview and challenges

W Wang, Q Yao, F Teng, J Cui, J Dong, Y Wei - Biomedicine & …, 2021 - Elsevier
Although considerable advance has been made in diagnosing and treating, asthma is still a
serious public health challenge. Traditional Chinese medicine (TCM) is an effective therapy …