Oleanolic acid: extraction, characterization and biological activity

JM Castellano, S Ramos-Romero, JS Perona - Nutrients, 2022 - mdpi.com
Oleanolic acid, a pentacyclic triterpenoid ubiquitously present in the plant kingdom, is
receiving outstanding attention from the scientific community due to its biological activity …

Metabolomics: A scoping review of its role as a tool for disease biomarker discovery in selected non-communicable diseases

AV Aderemi, AO Ayeleso, OO Oyedapo, E Mukwevho - Metabolites, 2021 - mdpi.com
Metabolomics is a branch of 'omics' sciences that utilises a couple of analytical tools for the
identification of small molecules (metabolites) in a given sample. The overarching goal of …

[HTML][HTML] Prophylactic and therapeutic roles of oleanolic acid and its derivatives in several diseases

A Sen - World Journal of Clinical Cases, 2020 - ncbi.nlm.nih.gov
Oleanolic acid (OA) and its derivatives are widely found in diverse plants and are naturally
effective pentacyclic triterpenoid compounds with broad prophylactic and therapeutic roles …

Development and evaluation of oleanolic acid dosage forms and its derivatives

A Feng, S Yang, Y Sun, L Zhang… - BioMed Research …, 2020 - Wiley Online Library
Oleanolic acid is a pentacyclic triterpenoid compound that exists widely in medicinal herbs
and other plants. Because of the extensive pharmacological activity, oleanolic acid has …

The effect and mechanism of oleanolic acid in the treatment of metabolic syndrome and related cardiovascular diseases

Q Luo, Y Wei, X Lv, W Chen, D Yang, Q Tuo - Molecules, 2024 - mdpi.com
Metabolic syndromes (MetS) and related cardiovascular diseases (CVDs) pose a serious
threat to human health. MetS are metabolic disorders characterized by obesity, dyslipidemia …

Long-term impact of neonatal intake of oleanolic acid on the expression of AMP-activated protein kinase, adiponectin and inflammatory cytokines in rats fed with a …

MG Matumba, AO Ayeleso, T Nyakudya, K Erlwanger… - Nutrients, 2019 - mdpi.com
AMP-activated protein kinase (AMPK) is known to regulate both glucose and lipid
metabolism, which play vital roles in the development of metabolic syndrome. One way of …

Potential protective effect of oleanolic acid on the components of metabolic syndrome: a systematic review

Á Fernández-Aparicio, J Schmidt-RioValle… - Journal of Clinical …, 2019 - mdpi.com
The high prevalence of obesity is a serious public health problem in today's world. Both
obesity and insulin resistance favor the development of metabolic syndrome (MetS), which is …

[HTML][HTML] Assessing the impact of concurrent high-fructose and high-saturated fat diets on pediatric metabolic syndrome: A review

MA Vargas-Vargas, M González-Montoya… - World Journal of …, 2024 - wjgnet.com
High-saturated fat (HF) or high-fructose (HFr) consumption in children pre dispose them to
metabolic syndrome (MetS). In rodent models of MetS, diets containing individually HF or …

Potential protective effects of neonatal supplementation with oleanolic acid on peroxisome proliferator-activated receptor gamma (PPARγ)-ligand dependent …

M Mosana, A Ayeleso, T Nyakudya… - Natural Product …, 2020 - journals.sagepub.com
The effect of neonatal oral supplementation of oleanolic acid (OA) on peroxisome
proliferator-activated receptor gamma (PPARγ)-1 on glucose homeostasis in high fructose …

Modulating the surface properties of metallic implants and the response of breast cancer cells by surface relief induced via bulk plastic deformation

B Uzer - Frontiers in Materials, 2020 - frontiersin.org
Micro/nanoscale textured surfaces have presented promising tissue–implant integration via
increasing surface roughness, energy, and wettability. Recent studies indicate that surface …