Pain and immunity: implications for host defence
Pain is a hallmark of tissue injury, inflammatory diseases, pathogen invasion and
neuropathy. It is mediated by nociceptor sensory neurons that innervate the skin, joints …
neuropathy. It is mediated by nociceptor sensory neurons that innervate the skin, joints …
Nociceptor sensory neuron–immune interactions in pain and inflammation
Nociceptor sensory neurons protect organisms from danger by eliciting pain and driving
avoidance. Pain also accompanies many types of inflammation and injury. It is increasingly …
avoidance. Pain also accompanies many types of inflammation and injury. It is increasingly …
[HTML][HTML] Somatotopic organization and intensity dependence in driving distinct NPY-expressing sympathetic pathways by electroacupuncture
S Liu, ZF Wang, YS Su, RS Ray, XH Jing, YQ Wang… - Neuron, 2020 - cell.com
The neuroanatomical basis behind acupuncture practice is still poorly understood. Here, we
used intersectional genetic strategy to ablate NPY+ noradrenergic neurons and/or adrenal …
used intersectional genetic strategy to ablate NPY+ noradrenergic neurons and/or adrenal …
Neuronal regulation of immunity: why, how and where?
M Schiller, TL Ben-Shaanan, A Rolls - Nature Reviews Immunology, 2021 - nature.com
Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …
reason; it fills the gap between two principal systems of the organism, the nervous system …
Inflammation, cancer and immunity—implication of TRPV1 channel
JK Bujak, D Kosmala, IM Szopa, K Majchrzak… - Frontiers in …, 2019 - frontiersin.org
Process of inflammation and complex interactions between immune and cancer cells within
tumor microenvironment are known to drive and shape the outcome of the neoplastic …
tumor microenvironment are known to drive and shape the outcome of the neoplastic …
A cross-sectional study of cannabidiol users
J Corroon, JA Phillips - Cannabis and cannabinoid research, 2018 - liebertpub.com
Introduction: Preclinical and clinical studies suggest that cannabidiol (CBD) found in
Cannabis spp. has broad therapeutic value. CBD products can currently be purchased …
Cannabis spp. has broad therapeutic value. CBD products can currently be purchased …
Calcitonin gene-related peptide: physiology and pathophysiology
FA Russell, R King, SJ Smillie, X Kodji… - Physiological …, 2014 - journals.physiology.org
Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …
Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia
Lung-innervating nociceptor sensory neurons detect noxious or harmful stimuli and
consequently protect organisms by mediating coughing, pain, and bronchoconstriction …
consequently protect organisms by mediating coughing, pain, and bronchoconstriction …
Bacteria activate sensory neurons that modulate pain and inflammation
Nociceptor sensory neurons are specialized to detect potentially damaging stimuli,
protecting the organism by initiating the sensation of pain and eliciting defensive …
protecting the organism by initiating the sensation of pain and eliciting defensive …
Neuroimmunity: physiology and pathology
Evolution has yielded multiple complex and complementary mechanisms to detect
environmental danger and protect tissues from damage. The nervous system rapidly …
environmental danger and protect tissues from damage. The nervous system rapidly …