In principle, proton therapy offers a substantial clinical advantage over conventional photon
therapy. This is because of the unique depth-dose characteristics of protons, which can be …

Chordoma is a rare bone cancer that is aggressive, locally invasive, and has a poor
prognosis. Chordomas are thought to arise from transformed remnants of notochord and …

Chordomas are very rare bone malignant tumours that have had a shortage of effective
treatments for a long time. New treatments are now available for both the local and the …

Chordomas are rare, malignant bone tumors of the skull-base and axial skeleton. Until
recently, there was no consensus among experts regarding appropriate clinical …

Particle beams like protons and heavier ions offer improved dose distributions compared
with photon (also called x-ray) beams and thus enable dose escalation within the tumor …

Chordomas are rare, slowly growing, locally aggressive neoplasms of bone that arise from
embryonic remnants of the notochord. These tumors typically occur in the axial skeleton and …

Purpose: The impact of different local therapy approaches on local control, event-free
survival, and secondary malignancies in the CESS 81, CESS 86, and EICESS 92 trials was …

Proton beam therapy (PBT) is a novel method for treating malignant disease with
radiotherapy. The purpose of this work was to evaluate the state of the science of PBT and …

BACKGROUND AND PURPOSE: Relative to X-ray beams, proton [1H] and carbon ion [12C]
beams provide superior distributions due primarily to their finite range. The principal …

Use of proton beam therapy has expanded, with the number of proton centres rapidly
increasing not only in the USA but also worldwide. The physical characteristics of the proton …