Benzimidazoles in helminthiasis chemotherapy: Developments and challenges

P Pattanayak, D Panigrahi, S Kumari, HN Yadav… - Journal of Molecular …, 2024 - Elsevier
Globally, helminthiasis is one of the most prevalent causes of mortality and morbidity and
threatens humans and livestock. An effective anthelmintic vaccine is also lacking. As a …

A New Indole Derivative from the Red Alga Chondria atropurpurea. Isolation, Structure Determination, and Anthelmintic Activity

D Davyt, W Entz, R Fernandez… - Journal of natural …, 1998 - ACS Publications
Chondriamide C (3), a new bis (indole) amide, was isolated from the red alga Chondria
atropurpurea, and its structure was established from spectroscopic data and chemical …

New Sesquiterpene Derivatives from the Red Alga Laurencia scoparia. Isolation, Structure Determination, and Anthelmintic Activity

D Davyt, R Fernandez, L Suescun… - Journal of Natural …, 2001 - ACS Publications
Eleven sesquiterpenes (1− 11) and one long chain aldehyde (12) have been isolated from
the dichloromethane extract of the red alga Laurencia scoparia. Four of them are new …

MUCIN-TYPE O-GLYCOSYLATION IN HELMINTH PARASITES FROM MAJOR TAXONOMIC GROUPS: EVIDENCE FOR WIDESPREAD DISTRIBUTION OF THE TN ANTIGEN …

C Casaravilla, T Freire, R Malgor… - Journal of …, 2003 - meridian.allenpress.com
This article focuses on the initiation pathway of mucin-type O-glycosylation in helminth
parasites. The presence of the GalNAc-O-Ser/Thr structure, also known as Tn antigen, a …

Bisabolanes from the Red Alga Laurencia scoparia

D Davyt, R Fernandez, L Suescun… - Journal of natural …, 2006 - ACS Publications
Three novel halogenated β-bisabolene sesquiterpenoids (1− 3), together with two know
triquinane alcohol sesquiterpenes (6 and 7), were isolated from the red alga Laurencia …

Characterization of the carcinoma-associated Tk antigen in helminth parasites

L Ubillos, A Medeiros, M Cancela, C Casaravilla… - Experimental …, 2007 - Elsevier
Expression of Tk antigen, a truncated carbohydrate antigen, was examined in helmith
parasites. Using the monoclonal antibody LM389, this antigen was detected in extracts from …

Unusual terpenylated acylphloroglucinols from Dryopteris wallichiana

C Socolsky, L Domínguez, Y Asakawa, A Bardón - Phytochemistry, 2012 - Elsevier
Four unusual terpenylated acylphloroglucinols were isolated from the diethyl ether extract of
the scales and rhizomes of the fern Dryopteris wallichiana together with the known …

Synthesis and anthelmintic evaluation of novel valerolactam-benzimidazole hybrids

B Munguía, P Mendina, R Espinosa… - Letters in Drug …, 2013 - benthamdirect.com
Some novel valerolactam derivatives of 5 (6)-substituted-(1H-benzimidazol-2-yl-amine)
were constructed based on the union of two structural domains with anthelmintic activity. The …

Deoxo-Fluor-mediated cyclodehydration of β-hydroxy thioamides to the corresponding thiazolines

SG Mahler, GL Serra, D Antonow, E Manta - Tetrahedron Letters, 2001 - Elsevier
Deoxo-Fluor-mediated cyclodehydration of β-hydroxy thioamides to the corresponding
thiazolines - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …

Synthesis and biological evaluation of simplified mycothiazole analogues

G Mahler, G Serra, S Dematteis, J Saldaña… - Bioorganic & medicinal …, 2006 - Elsevier
Thiazoline and oxazoline analogues of the natural product mycothiazole were synthesized
from a common intermediate and evaluated in vitro against HCT-15 colon cancer cells and …