[PDF][PDF] Molecular aspects of fructose metabolism and metabolic disease

MA Herman, MJ Birnbaum - Cell metabolism, 2021 - cell.com
Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …

[HTML][HTML] “Sweet death”: fructose as a metabolic toxin that targets the gut-liver axis

MA Febbraio, M Karin - Cell metabolism, 2021 - cell.com
Glucose and fructose are closely related simple sugars, but fructose has been associated
more closely with metabolic disease. Until the 1960s, the major dietary source of fructose …

Dietary fructose and fructose-induced pathologies

S Jung, H Bae, WS Song, C Jang - Annual review of nutrition, 2022 - annualreviews.org
The consumption of fructose as sugar and high-fructose corn syrup has markedly increased
during the past several decades. This trend coincides with the exponential rise of metabolic …

[HTML][HTML] Glucose transporters in the small intestine in health and disease

H Koepsell - Pflügers Archiv-European Journal of Physiology, 2020 - Springer
Absorption of monosaccharides is mainly mediated by Na+-d-glucose cotransporter SGLT1
and the facititative transporters GLUT2 and GLUT5. SGLT1 and GLUT2 are relevant for …

[HTML][HTML] Fructose metabolism and metabolic disease

SA Hannou, DE Haslam, NM McKeown… - The Journal of …, 2018 - Am Soc Clin Investig
Increased sugar consumption is increasingly considered to be a contributor to the worldwide
epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of …

Intestinal absorption of fructose

RP Ferraris, J Choe, CR Patel - Annual review of nutrition, 2018 - annualreviews.org
Increased understanding of fructose metabolism, which begins with uptake via the intestine,
is important because fructose now constitutes a physiologically significant portion of human …

[HTML][HTML] Intestinal fructose and glucose metabolism in health and disease

B Merino, CM Fernández-Díaz, I Cózar-Castellano… - Nutrients, 2019 - mdpi.com
The worldwide epidemics of obesity and diabetes have been linked to increased sugar
consumption in humans. Here, we review fructose and glucose metabolism, as well as …

[HTML][HTML] The role of fructose in non-alcoholic steatohepatitis: old relationship and new insights

A Federico, V Rosato, M Masarone, P Torre, M Dallio… - Nutrients, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) represents the result of hepatic fat overload not
due to alcohol consumption and potentially evolving to advanced fibrosis, cirrhosis, and …

[HTML][HTML] Nutritional treatment in Crohn's disease

G Caio, L Lungaro, F Caputo, E Zoli, F Giancola… - Nutrients, 2021 - mdpi.com
Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) which can affect any
part of the whole gastrointestinal tract (from mouth to anus). Malnutrition affects 65–75% of …

Tissue-specific fructose metabolism in obesity and diabetes

RN Helsley, F Moreau, MK Gupta, A Radulescu… - Current diabetes …, 2020 - Springer
Abstract Purpose of Review The objective of this review is to provide up-to-date and
comprehensive discussion of tissue-specific fructose metabolism in the context of diabetes …