The Turing, or reaction-diffusion (RD), model is one of the best-known theoretical models
used to explain self-regulated pattern formation in the developing animal embryo. Although …

One of the most fundamental questions in biology is that of biological pattern: how do the
structures and shapes of organisms arise? Undoubtedly, the two most influential ideas in …

Abstract β-Catenin is an essential molecule in Wnt/wingless signaling, which controls
decisive steps in embryogenesis. To study the role of β-catenin in skin development, we …

Hair follicle morphogenesis is initiated by a dermal signal that induces the development of
placodes in the overlying epithelium. To determine whether WNT signals are required for …

Clinical conditions causing hair loss, such as androgenetic alopecia, alopecia areata, and
scarring alopecia, can be psychologically devastating to individuals and are the target of a …

The epidermis and its appendages develop from a single layer of multipotent embryonic
progenitor keratinocytes. Embryonic stem cells receive cues from their environment that …

Mammalian dentition consists of teeth that develop as discrete organs. From anterior to
posterior, the dentition is divided into regions of incisor, canine, premolar and molar tooth …

In 1972, we proposed a theory of biological pattern formation in which concentration maxima
of pattern forming substances are generated through local self‐enhancement in conjunction …

Mathematical reaction-diffusion models have been suggested to describe formation of
animal pigmentation patterns and distribution of epidermal appendages. However, the …

The pigment patterns on tropical shells are of great beauty and diversity. Their mixture of
regularity and irregularity is fascinating. A particular pattern seems to follow particular rules …