Pathophysiology of varicocele in male infertility in the era of assisted reproductive technology

K Shiraishi, H Matsuyama… - International journal of …, 2012 - Wiley Online Library
Varicocele is the most common and treatable cause of male infertility. Studies of a rat
experimental left varicocele model and human testicular biopsy samples have shown the …

[PDF][PDF] Molecular and other predictors for infertility in patients with varicoceles

S Benoff, JL Marmar, IR Hurley - Front Biosci, 2009 - article.imrpress.com
Definition 3. Frequency of occurrence and presentation 3.1. Association with infertility and
current treatment 4. The varicocele controversy 5. Potential mechanisms 6. Deficits already …

[HTML][HTML] Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle

D Murta, M Batista, E Silva, A Trindade, D Henrique… - PloS one, 2013 - journals.plos.org
The transcription and expression patterns of Notch pathway components (Notch 1–3, Delta1
and 4, Jagged1) and effectors (Hes1, Hes2, Hes5 and Nrarp) were evaluated (through RT …

Differential Notch1 and Notch2 expression and frequent activation of Notch signaling in gastric cancers

Y Sun, X Gao, J Liu, QY Kong… - … of pathology & …, 2011 - meridian.allenpress.com
Context.—The biologic effects of Notch1 and Notch2 vary with cancer types and their
potential role (s) in gastric cancers (GCs) remains largely unknown. Objectives.—This study …

精索静脉曲张致不育机制研究进展

吕逸清, 陈斌 - 中华男科学杂志, 2008 - cqvip.com
精索静脉曲张(VC) 是男性泌尿生殖系统中常见的疾病之一, 近年来精索静脉曲张对男性生育的
影响越来越受重视. 目前对精索静脉曲张致男性不育的机制已进行了不少研究 …

NOTCH signaling in Sertoli cells regulates gonocyte fate

TX Garcia, MC Hofmann - Cell cycle, 2013 - Taylor & Francis
Gonocytes (or prospermatogonia) are the precursors to spermatogonial stem cells (SSCs),
which provide the foundation for spermatogenesis through their ability to both self-renew …

[HTML][HTML] In Vivo Notch Signaling Blockade Induces Abnormal Spermatogenesis in the Mouse

D Murta, M Batista, A Trindade, E Silva, D Henrique… - PloS one, 2014 - journals.plos.org
In a previous study we identified active Notch signaling in key cellular events occurring at
adult spermatogenesis. In this study, we evaluated the function of Notch signaling in …

Segregation of spermatozoa within sperm storage tubules of fowl and turkey hens

LM King, JP Brillard, WM Garrett, MR Bakst… - …, 2002 - rep.bioscientifica.com
Sertoli cells and germ cells are separated from the interstitial blood capillaries by an
extracellular matrix and the peritubular cells, which constitute a barrier to the movement of …

Distribution of Notch family proteins in intrauterine growth restriction and hypertension complicated human term placentas

Z Sahin, N Acar, O Ozbey, I Ustunel, R Demir - Acta histochemica, 2011 - Elsevier
Members of the Notch family have been detected in many developmental and cell
specification processes during placental development. However, Notch protein expression …

Potential Involvement of DNA Methylation in Hybrid Sterility in Hermaphroditic Argopecten Scallops

T Yu, J Ning, M Chen, F Wang, G Liu, Q Wang, X Xu… - Marine …, 2023 - Springer
DNA methylation is an important epigenetic modification factor in regulating fertility.
Corresponding process remains poorly investigated in hermaphroditic scallops. The …