GATA1 is considered as the “master” transcription factor in erythropoiesis. It regulates at the
transcriptional level all aspects of erythroid maturation and function, as revealed by gene …

Abstract Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVaGC) is a recently
recognized entity, which is defined by the presence of EBV in the gastric carcinoma cells …

Background MicroRNAs are a class of small non-coding RNAs that regulate mRNA
expression at the post-transcriptional level and thereby many fundamental biological …

GATA1 is a prototypical lineage-restricted transcription factor that is central to the correct
differentiation, proliferation and apoptosis of erythroid and megakaryocytic cells. Mutations …

Regulatory mechanisms that govern lineage specification of the mesodermal progenitors to
become endothelial and hematopoietic cells remain an area of intense interest. Both Ets and …

Strict regulations of the Gata1 and Gata2 genes are critical for proper lineage commitment
and development of erythroid cells. It has been shown in transgenic mouse analyses that cis …

How cell proliferation subsides as cells terminally differentiate remains largely enigmatic,
although this phenomenon is central to the existence of multicellular organisms. Here, we …

The transcription factors GATA1 and GATA2 are fundamental regulators of hematopoiesis
and have overlapping expression profiles. GATA2 is expressed in hematopoietic stem cells …

To investigate the clinicopathologic features, Epstein–Barr virus (EBV) latency pattern and
genome polymorphism of EBV‐associated gastric carcinoma (EBVaGC) in Guangzhou, an …

We analyse here the definition of the gene in order to distinguish, on the basis of modern
insight in molecular biology, what the gene is coding for, namely a specific polypeptide, and …