Hybrid species have more genetic diversity than their parents. However, the impact of the
hybrid genome of reciprocal crosses on brain function remains largely unknown. We …

Recent studies have demonstrated that epigenetic modifications are deeply involved in
neurogenesis; however, the precise mechanisms remain largely unknown. To determine the …

The lack of a widely accessible method for expressing genes of interest in wild-type embryos
is a fundamental obstacle to understanding genetic regulation during embryonic …

Here, we present a protocol for differential multi-omic analyses of distinct cell types in the
developing mouse cerebral cortex. We describe steps for in utero electroporation …

Microglia, resident immune cells in the central nervous system, undergo morphological and
functional changes in response to signals from the local environment and mature into …

Dynamic changes in histone modifications mediated by Polycomb group proteins can be
indicative of the transition of gene repression mode during development. Here, we present …

During the early stage of mammalian neural development, neuroepithelial cells (NECs)
proliferate and increase their pool size before switching their fate to become neurogenic …