Advances in materials-based therapeutic strategies against osteoporosis

C Lei, J Song, S Li, Y Zhu, M Liu, M Wan, Z Mu, FR Tay… - Biomaterials, 2023 - Elsevier
Osteoporosis is caused by the disruption in homeostasis between bone formation and bone
resorption. Conventional management of osteoporosis involves systematic drug …

[HTML][HTML] Strontium functionalized in biomaterials for bone tissue engineering: A prominent role in osteoimmunomodulation

J You, Y Zhang, Y Zhou - Frontiers in Bioengineering and …, 2022 - frontiersin.org
With the development of bone tissue engineering bio-scaffold materials by adding metallic
ions to improve bone healing have been extensively explored in the past decades …

[HTML][HTML] Bioinspired silk fibroin materials: From silk building blocks extraction and reconstruction to advanced biomedical applications

X Yao, S Zou, S Fan, Q Niu, Y Zhang - Materials Today Bio, 2022 - Elsevier
Silk fibroin has become a promising biomaterial owing to its remarkable mechanical
property, biocompatibility, biodegradability, and sufficient supply. However, it is difficult to …

Ion incorporation into bone grafting materials

Q Zhao, Y Ni, H Wei, Y Duan, J Chen… - Periodontology …, 2024 - Wiley Online Library
The use of biomaterials in regenerative medicine has expanded to treat various disorders
caused by trauma or disease in orthopedics and dentistry. However, the treatment of large …

[HTML][HTML] Development and challenges of cells-and materials-based tooth regeneration

Z Fu, Y Zhuang, J Cui, R Sheng, H Tomás… - Engineered …, 2022 - Elsevier
Tooth defect and loss are common clinical diseases in stomatology. With the extension of life
expectancy, there is an increasing demand for tooth tissue and whole tooth regeneration …

[HTML][HTML] Osteoimmunomodulatory bioinks for 3D bioprinting achieve complete regeneration of critical-sized bone defects

X Yu, S Jiang, D Li, SGF Shen, X Wang, K Lin - Composites Part B …, 2024 - Elsevier
Regeneration the critical-sized bone defects remains a great challenge to clinical therapy
due to the inflammatory microenvironment and lack of stem cells in the region of the bone …

[HTML][HTML] Recent advance of strontium functionalized in biomaterials for bone regeneration

X Liu, H Huang, J Zhang, T Sun, W Zhang, Z Li - Bioengineering, 2023 - mdpi.com
Bone defect disease causes damage to people's lives and property, and how to effectively
promote bone regeneration is still a big clinical challenge. Most of the current repair …

[HTML][HTML] VEGF-Loaded Heparinised Gelatine-Hydroxyapatite-Tricalcium Phosphate Scaffold Accelerates Bone Regeneration via Enhancing Osteogenesis …

X Chen, CY Gao, XY Chu, CY Zheng… - … in Bioengineering and …, 2022 - frontiersin.org
Background: Bone tissue defect, one of the common orthopaedicdiseases, is traumatizing
and affects patient's lifestyle. Although autologous and xenograft bone transplantations are …

[HTML][HTML] Icariin self-crosslinked network functionalized strontium-doped bioceramic scaffolds synergistically enhanced the healing of osteoporotic bone defects

T Song, J Yang, P Liu, M Liu, D Li, Y Xiao… - Composites Part B …, 2022 - Elsevier
The regeneration of osteoporotic defects remains a great challenge in clinic, due to the
capacity of bone regeneration is seriously impaired and bone resorption is overactivated …

Engineered nanostructure fibrous cell-laden biointerfaces integrating Fe3O4/SrO2-fMWCNTs induce osteogenesis and anti-bacterial effect

R Kandel, SR Jang, U Ghimire, S Shrestha… - Journal of Industrial and …, 2023 - Elsevier
Improving biomechanical and biochemical properties of tissue-engineered scaffolds akin to
those of native stem-cell niches can effectively regenerate tissues. Bio-ceramic …