Medial vascular calcification has emerged as a putative key factor contributing to the
excessive cardiovascular mortality of patients with chronic kidney disease (CKD) …

Patients with chronic kidney disease (CKD) are at a highly increased risk of cardiovascular
complications, with increased vascular inflammation, accelerated atherogenesis and …

Arterial medial calcification (AMC) is prevalent in patients with chronic kidney disease (CKD)
and contributes to elevated risk of cardiovascular events and mortality. Vascular smooth …

The Transforming Growth Factor beta (TGFβ) and Bone Morphogenic Protein (BMP)
pathways intersect at multiple signaling hubs and cooperatively or counteractively …

Magnesium reduces vascular smooth muscle cell (VSMC) calcification in vitro but the
mechanism has not been revealed so far. This work used only slightly increased magnesium …

For more than a decade, the Wnt–β-catenin pathway has been the focus of intense basic
and clinical research in the bone field because of its importance in skeletal development …

The Wnt/β-catenin signaling pathway is abnormally activated in most colorectal cancers and
in a proportion of other neoplasias. This activation initiates or contributes to carcinogenesis …

Patients with chronic kidney disease (CKD) are at increased risk of osteoporosis and
vascular calcification. Bone demineralization and vascular mineralization go often hand in …

At the early stage of chronic kidney disease (CKD), the systemic mineral metabolism and
bone composition start to change. This alteration is known as chronic kidney disease …

Background: Vascular calcification (VC), in which vascular smooth muscle cells (VSMCs)
undergo a phenotypic transformation into osteoblast-like cells, is one of the emergent risk …