The Brassicaceae family, known as cruciferous vegetables, includes many economically
important species, mainly edible oil plants, vegetable species, spice plants, and feed plants …

Peptidyl-prolyl cis/trans isomerase family (PPIase) is structurally divided into three
subfamilies, cyclophilins (Cyps), FK506-binding proteins (FKBPs), and parvulins. Pin1 …

Background Radiotherapy (RT) is a highly effective multimodal nonsurgical treatment that is
essential for patients with advanced colorectal cancer (CRC). Nevertheless, cell …

To identify new genetic factors for colorectal cancer (CRC), we conducted a genome-wide
association study in east Asians. By analyzing genome-wide data in 2,098 cases and 5,749 …

Background Previous work has shown reduced expression levels of let-7 in lung tumors. But
little is known about the expression or mechanisms of let-7a in prostate cancer. In this study …

Background & Aims Indoleamine 2, 3 dioxygenase-1 (IDO1) catabolizes tryptophan along
the kynurenine pathway. Although IDO1 is expressed in inflamed and neoplastic epithelial …

Because of the poor prognosis and the development of resistance against chemotherapeutic
drugs, the current treatment for advanced metastatic colorectal cancer (CRC) is ineffective …

To identify common variants influencing colorectal cancer (CRC) risk, we performed a meta-
analysis of five genome-wide association studies, comprising 5626 cases and 7817 controls …

Alternative polyadenylation (APA) contributes to transcriptome complexity by generating
mRNA isoforms with varying 3′ UTR lengths. APA leading to 3′ UTR shortening (3′ US) …

Sulforaphane (SFN), an isothiocyanate derived from cruciferous vegetables, induces potent
anti-proliferative effects in prostate cancer cells. One mechanism that may contribute to the …