Nanomaterials (NMs) have revolutionized multiple aspects of medicine by enabling novel
sensing, diagnostic, and therapeutic approaches. Advancements in processing and …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has grown to be a global
public health crisis with no safe and effective treatments available yet. Recent findings …

The strategy of using mesenchymal stem cells (MSCs) as a living carrier for active delivery of
therapeutic agents targeting tumor sites has been attempted in a wide range of studies to …

Background Malignant behavior and radioresistance, which severely limits the efficacy of
radiation therapy (RT) in nasopharyngeal carcinoma (NPC), are associated with tumor …

Pyroptosis is closely associated with cancer development; however, the role of pyroptosis in
pancreatic ductal adenocarcinoma (PDAC), a fatal malignant tumour with a poor overall …

Mesenchymal stem/stromal cells (MSCs) are multipotent cells involved in numerous
physiological events, including organogenesis, the maintenance of tissue homeostasis …

Radiotherapy (RT) mainly elicits antitumor immunity via the cGAS/STING axis for type I
interferon (IFN) production. However, dysregulation of cGAS/STING constrains radiotherapy …

TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), also known as APO2L,
belongs to the tumor necrosis factor family. By binding to the death receptor 4 (DR4) or DR5 …

TNF-related apoptosis-inducing ligand (TRAIL) selectively induces the apoptosis pathway in
tumor cells leading to tumor cell death. Because TRAIL induction can kill tumor cells, cancer …

Pro-inflammatory cytokines can effectively be used for tumor immunotherapy, affecting every
step of the tumor immunity cycle. Thereby, they can restore antigen priming, improve the …