Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

Post-exposure treatments for Ebola and Marburg virus infections

RW Cross, CE Mire, H Feldmann… - Nature Reviews Drug …, 2018 - nature.com
The filoviruses—Ebola virus and Marburg virus—cause lethal haemorrhagic fever in
humans and non-human primates (NHPs). Filoviruses present a global health threat both as …

Ebola and Marburg virus vaccines

P Reynolds, A Marzi - Virus Genes, 2017 - Springer
The filoviruses, Ebola virus (EBOV), and Marburg virus (MARV), are among the most
pathogenic viruses known to man and the causative agents of viral hemorrhagic fever …

In silico-based vaccine design against Ebola virus glycoprotein

R Dash, R Das, M Junaid, MFC Akash… - … and Applications in …, 2017 - Taylor & Francis
Ebola virus (EBOV) is one of the lethal viruses, causing more than 24 epidemic outbreaks to
date. Despite having available molecular knowledge of this virus, no definite vaccine or …

Adenoviral vector-based vaccines and gene therapies: current status and future prospects

S Singh, R Kumar, B Agrawal - Adenoviruses, 2019 - books.google.com
Adenoviruses are one of the most genetically diverse DNA viruses and cause non-
lifethreatening infections in the ocular, respiratory, or gastrointestinal epithelium of a diverse …

Conserved B and T cell epitopes prediction of ebola virus glycoprotein for vaccine development: an immuno-informatics approach

B Ahmad, UA Ashfaq, M Rahman, MS Masoud… - Microbial …, 2019 - Elsevier
Ebola virus (EBOV), a non-segmented single-stranded RNA virus, is often-most transmitted
through body fluids like sweat, tears, saliva, and nasal secretions. Till date, there is no …

Vaccines against Ebola virus and Marburg virus: recent advances and promising candidates

JJ Suschak, CS Schmaljohn - Human Vaccines & …, 2019 - Taylor & Francis
The filoviruses Ebola virus and Marburg virus are among the most dangerous pathogens in
the world. Both viruses cause viral hemorrhagic fever, with case fatality rates of up to 90 …

Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control

S Wang, W Li, Z Wang, W Yang, E Li, X Xia… - … and Targeted Therapy, 2024 - nature.com
To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …

Animal models in human adenovirus research

LD Bertzbach, WH Ip, T Dobner - Biology, 2021 - mdpi.com
Simple Summary Animal models are widely used to study various aspects of human
diseases and disorders. Likewise, they are indispensable for preclinical testing of medicals …

Ebola: lessons on vaccine development

H Feldmann, F Feldmann, A Marzi - Annual review of …, 2018 - annualreviews.org
The West African Ebola virus (EBOV) epidemic has fast-tracked countermeasures for this
rare, emerging zoonotic pathogen. Until 2013–2014, most EBOV vaccine candidates were …