Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …

Tumor-specific, circulating cell-free DNA in liquid biopsies is a promising source of
biomarkers for minimally invasive serial monitoring of treatment responses in cancer …

Mitochondria are considered as the power‐generating units of the cell due to their key role
in energy metabolism and cell signaling. However, mitochondrial components could be …

An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …

Liquid biopsy recently became a very promising diagnostic method that has several
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …

Widespread adaptation of liquid biopsy for the early detection of cancer has yet to reach
clinical utility. Circulating tumor DNA is commonly detected though the presence of genetic …

Nucleic acid is the main material for storing, copying, and transmitting genetic information.
Gene sequencing is of great significance in DNA damage research, gene therapy, mutation …

Since the detection of cell‐free DNA (cfDNA) in human plasma in 1948, it has been
investigated as a non‐invasive screening tool for many diseases, especially solid tumours …

Background The integration of biological, psychological, and social factors in medicine has
benefited from increasingly precise stress response biomarkers. Mitochondria, a subcellular …

The understanding of mechanisms linking psychological stress to disease risk depend on
reliable stress biomarkers. Circulating cell-free DNA (cfDNA) has emerged as a potential …