In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

Most chronic inflammatory illnesses include fibrosis as a pathogenic characteristic.
Extracellular matrix (ECM) components build up in excess to cause fibrosis or scarring. The …

CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …

Enhancers play a central role in the spatiotemporal control of gene expression and tend to
work in a cell-type-specific manner. In addition, they are suggested to be major contributors …

During acute infectious and inflammatory conditions, a large number of neutrophils are in
high demand as they are consumed in peripheral organs. The hematopoietic system rapidly …

Glycoprotein prostaglandin D2 synthase (PTGDS) is a member of the lipocalin superfamily
and plays dual roles in prostaglandins metabolism and lipid transport. PTGDS has been …

Hematopoietic stem cells (HSCs) ensure blood cell production during the life-time of an
organism, and to do so they need to balance self-renewal, proliferation, differentiation, and …

Platinum-taxane chemotherapy is the first-line standard-of-care treatment administered to
patients with epithelial ovarian cancer (EOC), and faces the major challenge of cisplatin …

Neutrophils, the most abundant innate immune cells, play essential roles in the innate
immune system. As key innate immune cells, neutrophils detect intrusion of pathogens and …

Our previous studies showed that dysregulation of the long noncoding RNA (lncRNA)
HOXA11-AS plays an important role in the development of glioma. However, the molecular …