Mechanisms underlying metabolic syndrome-related sarcopenia and possible therapeutic measures

ME Rubio-Ruiz, V Guarner-Lans… - International journal of …, 2019 - mdpi.com
Although there are several reviews that report the interrelationship between sarcopenia and
obesity and insulin resistance, the relation between sarcopenia and the other signs that …

Branched-chain amino acid metabolism in heart disease: an epiphenomenon or a real culprit?

Y Huang, M Zhou, H Sun, Y Wang - Cardiovascular research, 2011 - academic.oup.com
Metabolic remodelling is an integral part of the pathogenesis of heart failure. Although much
progress has been made in our current understanding of the metabolic impairment involving …

Deficient H2A. Z deposition is associated with genesis of uterine leiomyoma

DG Berta, H Kuisma, N Välimäki, M Räisänen, M Jäntti… - Nature, 2021 - nature.com
One in four women suffers from uterine leiomyomas (ULs)—benign tumours of the uterine
wall, also known as uterine fibroids—at some point in premenopausal life. ULs can cause …

The association of sarcopenia and visceral obesity with lean nonalcoholic fatty liver disease in Chinese patients with type 2 diabetes mellitus

X Zhang, Z He, Q Si, X Hu, L Yang, X Gu… - Journal of Diabetes …, 2022 - Wiley Online Library
Background. Few studies have specifically observed the relationship of sarcopenia, visceral
obesity, or their joint effects with lean NAFLD in patients with diabetes. We aimed to …

Thyroid hormone metabolism in innate immune cells

AH van der Spek, E Fliers… - Journal of …, 2017 - joe.bioscientifica.com
Klinefelter syndrome (KS) is the most common sex chromosomal disorder in males. Key
findings in older adolescents and young men are small testes with variable hypo …

Cardiac metabolism, reprogramming, and diseases

H Wang, M Shen, X Shu, B Guo, T Jia, J Feng… - Journal of …, 2024 - Springer
Cardiovascular diseases (CVD) account for the largest bulk of deaths worldwide, posing a
massive burden on societies and the global healthcare system. Besides, the incidence and …

Sarcopenic obesity: involvement of oxidative stress and beneficial role of antioxidant flavonoids

UJ Jung - Antioxidants, 2023 - mdpi.com
Sarcopenic obesity, which refers to concurrent sarcopenia and obesity, is characterized by
decreased muscle mass, strength, and performance along with abnormally excessive fat …

Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments

E Espino-Gonzalez, E Dalbram, R Mounier, J Gondin… - Cell Metabolism, 2024 - cell.com
Diabetes represents a major public health concern with a considerable impact on human life
and healthcare expenditures. It is now well established that diabetes is characterized by a …

Cerium oxide nanoparticles attenuate monocrotaline induced right ventricular hypertrophy following pulmonary arterial hypertension

MB Kolli, NDPK Manne, R Para, SK Nalabotu… - Biomaterials, 2014 - Elsevier
Cerium oxide (CeO 2) nanoparticles have been posited to exhibit potent anti-oxidant activity
which may allow for the use of these materials in biomedical applications. Herein, we …

Type 2 diabetes causes skeletal muscle atrophy but does not impair resistance training‐mediated myonuclear accretion and muscle mass gain in rats

S Ato, K Kido, K Sato, S Fujita - Experimental Physiology, 2019 - Wiley Online Library
New Findings What is the central question of this study? Type 2 diabetes mellitus (T2DM)
causes skeletal muscle atrophy; does it affect resistance training (RT)‐mediated molecular …