[HTML][HTML] The molecular basis of mammary gland development and epithelial differentiation
PF Slepicka, AVH Somasundara… - Seminars in cell & …, 2021 - Elsevier
Our understanding of the molecular events underpinning the development of mammalian
organ systems has been increasing rapidly in recent years. With the advent of new and …
organ systems has been increasing rapidly in recent years. With the advent of new and …
The variety of 3D breast cancer models for the study of tumor physiology and drug screening
E Fröhlich - International Journal of Molecular Sciences, 2023 - mdpi.com
Breast cancer is the most common cancer in women and responsible for multiple deaths
worldwide. 3D cancer models enable a better representation of tumor physiology than the …
worldwide. 3D cancer models enable a better representation of tumor physiology than the …
[HTML][HTML] Current status of breast organoid models
SC Mohan, TY Lee, AE Giuliano, X Cui - Frontiers in Bioengineering …, 2021 - frontiersin.org
Breast cancer (BC) is the most frequently diagnosed malignancy among women globally.
Although mouse models have been critical in advancing the knowledge of BC tumorigenesis …
Although mouse models have been critical in advancing the knowledge of BC tumorigenesis …
[HTML][HTML] Evolution of organoid technology: Lessons learnt in Co-Culture systems from developmental biology
In recent years, the development of 3D organoids has opened new avenues of investigation
into development, physiology, and regenerative medicine. Organoid formation and the …
into development, physiology, and regenerative medicine. Organoid formation and the …
In vitro assays for investigating the FLASH effect
FLASH radiotherapy is a novel technique that has been shown in numerous preclinical in
vivo studies to have the potential to be the next important improvement in cancer treatment …
vivo studies to have the potential to be the next important improvement in cancer treatment …
Models for translational proton radiobiology—from bench to bedside and back
T Suckert, S Nexhipi, A Dietrich, R Koch… - Cancers, 2021 - mdpi.com
Simple Summary An increasing number of cancer patients are treated with proton therapy.
Nevertheless, there are still open questions that require preclinical studies, for example …
Nevertheless, there are still open questions that require preclinical studies, for example …
Current and future perspectives of the use of organoids in radiobiology
PW Nagle, RP Coppes - Cells, 2020 - mdpi.com
The majority of cancer patients will be treated with radiotherapy, either alone or together with
chemotherapy and/or surgery. Optimising the balance between tumour control and the …
chemotherapy and/or surgery. Optimising the balance between tumour control and the …
Kidney organoid systems for studies of immune-mediated kidney diseases: challenges and opportunities
Acute and chronic kidney diseases are major contributors to morbidity and mortality in the
global population. Many nephropathies are considered to be immune-mediated with …
global population. Many nephropathies are considered to be immune-mediated with …
[HTML][HTML] Applications and perspectives of tumor organoids in radiobiology
J Yu, K Wang, Y Tang, D Zheng - Oncology Reports, 2024 - spandidos-publications.com
Radiotherapy exhibits significant versatility and efficacy in cancer treatment, thereby playing
a crucial role in the field of oncology. However, there remains an urgent need for extensive …
a crucial role in the field of oncology. However, there remains an urgent need for extensive …
Emerging biomimetic materials for studying tumor and immune cell behavior
LA Northcutt, A Suarez-Arnedo, M Rafat - Annals of biomedical …, 2020 - Springer
Cancer is one of the leading causes of death both in the United States and worldwide. The
dynamic microenvironment in which tumors grow consists of fibroblasts, immune cells …
dynamic microenvironment in which tumors grow consists of fibroblasts, immune cells …