In the early 1950s, Austin and Chang independently described the changes that are
required for the sperm to fertilize oocytes in vivo. These changes were originally grouped …

A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …

The cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins (CAP)
superfamily members are found in a remarkable range of organisms spanning each of the …

Morphological and biochemical studies have shown that autophagosomes fuse with
endosomes forming the so‐called amphisomes, a prelysosomal hybrid organelle. In the …

Intracellular Ca 2+ stores play a central role in the regulation of cellular [Ca 2+] i and the
generation of complex [Ca 2+] signals such as oscillations and waves. Ca 2+ signalling is of …

Thanks to a worrying decrease in male fertility, understanding how sperm'work'is a matter
both of interest and great importance. Sperm of all animals detect various environmental …

Spermatogenesis, an elaborate and male-specific process in adult testes by which a number
of spermatozoa are produced constantly for male fertility, relies on spermatogonial stem …

Fertilization is the process by which haploid gametes, sperm and egg, unite to produce a
genetically distinct individual. Interest in this area has exploded in recent years. Here are …

During capacitation, major changes take place in the sperm plasma membrane so as to
render it fusogenic and responsive to zona pellucida glycoproteins. However, the …

Progesterone is present at micromolar concentrations in the cumulus matrix, which
surrounds mammalian oocytes. Exposure of human spermatozoa to a concentration …