Founder mutations in Tunisia: implications for diagnosis in North Africa and Middle East

L Romdhane, R Kefi, H Azaiez, NB Halim… - Orphanet journal of rare …, 2012 - Springer
Abstract Background Tunisia is a North African country of 10 million inhabitants. The native
background population is Berber. However, throughout its history, Tunisia has been the site …

Contribution of common variants of ENPP1, IGF2BP2, KCNJ11, MLXIPL, PPARγ, SLC30A8 and TCF7L2 to the risk of type 2 diabetes in Lebanese and Tunisian Arabs

N Mtiraoui, A Turki, R Nemr, A Echtay, I Izzidi… - Diabetes & …, 2012 - Elsevier
BACKGROUND: While several type 2 diabetes mellitus (T2DM) susceptibility loci identified
through genome-wide association studies (GWAS) have been replicated in many …

Molecular diagnosis of distal renal tubular acidosis in Tunisian patients: proposed algorithm for Northern Africa populations for the ATP6V1B1, ATP6V0A4 and …

D Elhayek, G Perez de Nanclares, S Chouchane… - BMC medical …, 2013 - Springer
Background Primary distal renal tubular acidosis (dRTA) caused by mutations in the genes
that codify for the H+− ATPase pump subunits is a heterogeneous disease with a poor …

Clinical, immunological and genetic findings of a large Tunisian series of major histocompatibility complex class II deficiency patients

I Ben-Mustapha, K Ben-Farhat, N Guirat-Dhouib… - Journal of clinical …, 2013 - Springer
Introduction Major histocompatibility complex class II (MHC-II) expression deficiency is a
combined primary immunodeficiency leading to the impairment of the cellular and humoral …

On the origin of Iberomaurusians: new data based on ancient mitochondrial DNA and phylogenetic analysis of Afalou and Taforalt populations

R Kefi, M Hechmi, C Naouali, H Jmel… - … DNA Part A, 2018 - Taylor & Francis
Abstract The Western North African population was characterized by the presence of
Iberomaurusian civilization at the Epiplaeolithic period (around 20,000 years before present …

[PDF][PDF] Clinical and biochemical findings in Mexican patients with distal renal tubular acidosis

N Guerra-Hernández, M Matos-Martínez… - Rev Invest …, 2014 - researchgate.net
Introduction. Renal tubular acidosis (RTA) is a rare disease characterized by a normal
serum anion gap, sustained metabolic acidosis, low concentration of plasma bicarbonate …

Association between an angiotensin-converting enzyme gene polymorphism and Alzheimer's disease in a Tunisian population

N Fekih-Mrissa, I Bedoui, A Sayeh, H Derbali… - Annals of General …, 2017 - Springer
Background The angiotensin-converting enzyme gene (ACE) insertion/deletion (I/D or indel)
polymorphism has long been linked to Alzheimer's disease (AD), but the interpretation of …

[HTML][HTML] Anthropometry-Based Prediction Equation of Body Composition in a Population Aged 12–88 Years

K El Kari, A Mankai, DEL Kouki, S Mehdad… - The Journal of …, 2023 - Elsevier
Background Direct anthropometric measurements to assess body composition have limited
precision and/or specificity. Objectives The study aimed to develop a prediction equation …

Association between haptoglobin 2-2 genotype and coronary artery disease and its severity in a tunisian population

A Moussa, J Rejeb, A Omezzine, L Rebhi… - Biochemical …, 2014 - Springer
Haptoglobin (Hp) polymorphism generates three common human genotypes (Hp1-1, Hp2-1,
and Hp2-2), having functional differences, related to the risk of development of …

Alu insertion polymorphisms in the African Sahel and the origin of Fulani pastoralists

M Čížková, Z Hofmanová, MG Mokhtar… - Annals of Human …, 2017 - Taylor & Francis
Abstract Background: The origin of Western African pastoralism, represented today by the
Fulani nomads, has been a highly debated issue for the past decades, and has not yet been …