The microbiome in inflammatory bowel diseases: from pathogenesis to therapy

S Liu, W Zhao, P Lan, X Mou - Protein & cell, 2021 - academic.oup.com
Inflammatory bowel disease (IBD) has become a global disease with accelerating incidence
worldwide in the 21st century while its accurate etiology remains unclear. In the past …

Adherent-invasive Escherichia coli in inflammatory bowel disease

C Palmela, C Chevarin, Z Xu, J Torres, G Sevrin… - Gut, 2018 - gut.bmj.com
Intestinal microbiome dysbiosis has been consistently described in patients with IBD. In the
last decades, Escherichia coli, and the adherent-invasive E coli (AIEC) pathotype in …

[HTML][HTML] Dual role of microbiota-derived short-chain fatty acids on host and pathogen

R Mirzaei, E Dehkhodaie, B Bouzari, M Rahimi… - Biomedicine & …, 2022 - Elsevier
A growing body of documents shows microbiota produce metabolites such as short-chain
fatty acids (SCFAs) as crucial executors of diet-based microbial influence the host and …

Escherichia coli: an old friend with new tidings

J Vila, E Sáez-López, JR Johnson… - FEMS microbiology …, 2016 - academic.oup.com
Escherichia coli is one of the most-studied microorganisms worldwide but its characteristics
are continually changing. Extraintestinal E. coli infections, such as urinary tract infections …

Location is important: differentiation between ileal and colonic Crohn's disease

R Atreya, B Siegmund - Nature Reviews Gastroenterology & …, 2021 - nature.com
Crohn's disease can affect any part of the gastrointestinal tract; however, current European
and national guidelines worldwide do not differentiate between small-intestinal and colonic …

Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection

TJ Hannan, M Totsika, KJ Mansfield… - FEMS microbiology …, 2012 - academic.oup.com
Bladder infections affect millions of people yearly, and recurrent symptomatic infections
(cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …

The commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases

B Chassaing, A Darfeuille–Michaud - Gastroenterology, 2011 - Elsevier
Intestinal inflammation arises from abnormal host–microbe interactions. The perturbations of
homeostatic coexistence involve host genetic factors, barrier function, innate and adaptive …

CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

N Barnich, FA Carvalho, AL Glasser… - The Journal of …, 2007 - Am Soc Clin Investig
The ileal mucosa of Crohn disease (CD) patients is abnormally colonized by adherent-
invasive E. coli (AIEC) that are able to adhere to and invade intestinal epithelial cells. Here …

[HTML][HTML] Escherichia coli in chronic inflammatory bowel diseases: An update on adherent invasive Escherichia coli pathogenicity

M Martinez-Medina, LJ Garcia-Gil - World journal of …, 2014 - ncbi.nlm.nih.gov
Abstract Escherichia coli (E. coli), and particularly the adherent invasive E. coli (AIEC)
pathotype, has been increasingly implicated in the ethiopathogenesis of Crohn's disease …

Immunopathogenesis of inflammatory bowel disease

J Matricon, N Barnich, D Ardid - Self/nonself, 2010 - Taylor & Francis
Inflammatory bowel disease (IBD) is a group of idiopathic, chronic and relapsing
inflammatory conditions of the gastrointestinal tract. Familial and epidemiological studies …