Effectiveness of third-generation cephalosporins or piperacillin compared with cefepime or carbapenems for severe infections caused by wild-type AmpC β-lactamase …

A Maillard, T Delory, J Bernier, A Villa, K Chaibi… - International Journal of …, 2023 - Elsevier
Background The optimal treatment regimen for infections caused by wild-type AmpC β-
lactamase-producing Enterobacterales remains controversial. This study compared the …

Extended-Infusion β-Lactam Therapy, Mortality, and Subsequent Antibiotic Resistance Among Hospitalized Adults With Gram-Negative Bloodstream Infections

SM Karaba, SE Cosgrove, JH Lee, S Fiawoo… - JAMA Network …, 2024 - jamanetwork.com
Importance Current evidence is conflicting for associations of extended-infusion β-lactam (EI-
BL) therapy with clinical outcomes. Objective To investigate the association of EI-BL therapy …

Cefepime in vivo activity against carbapenem-resistant Enterobacterales that test as cefepime susceptible or susceptible-dose dependent in vitro: implications for …

A Fouad, CM Gill, PJ Simner, DP Nicolau… - Journal of …, 2023 - academic.oup.com
Abstract Background Carbapenem-resistant Enterobacterales (CRE) are a public health
concern. Among these isolates, there are reports of isolates that test as cefepime susceptible …

Long Story Short: Establishing Breakpoints for Antimicrobials and 2023 Updates

ML Bixby, D Zheng, EB Hirsch - Current Infectious Disease Reports, 2024 - Springer
Abstract Purpose of Review This review outlines the process of setting and revising Clinical
and Laboratory Standards Institute (CLSI) breakpoints and summarizes breakpoints …

[HTML][HTML] Cefepime vs carbapenems for treating third-generation cephalosporin-resistant AmpC β-lactamase-hyperproducing Enterobacterales bloodstream infections …

B Hoellinger, C Kaeuffer, P Boyer, N Lefebvre… - International Journal of …, 2023 - Elsevier
Objectives AmpC β-lactamase-hyperproducing Enterobacterales (ABLHE) bloodstream
infections (BSI) are emerging and leading to therapeutic challenges worldwide …

[PDF][PDF] First published 2024

JY Latif, BT Razak - 2024 - storage.unitedwebnetwork.com
CONSENSUS GUIDELINES ON TREATMENT OF MULTIDRUG RESISTANT GRAM NEGATIVES
Page 1 CONSENSUS GUIDELINES ON TREATMENT OF MULTIDRUG RESISTANT GRAM …