Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cells

P Mattar, K Bieback - Frontiers in immunology, 2015 - frontiersin.org
Mesenchymal stromal cells (MSC) have gained immense attraction in regenerative
medicine, tissue engineering, and immunotherapy. This is based on their differentiation …

Characteristics and clinical applications of Wharton's jelly-derived mesenchymal stromal cells

LL Liau, BHI Ruszymah, MH Ng, JX Law - Current research in translational …, 2020 - Elsevier
Mesenchymal stromal cells (MSCs) are widely used in the clinic because they involve fewer
ethical issues and safety concerns compared to other stem cells such as embryonic stem …

Therapeutic implications of human umbilical cord mesenchymal stromal cells in attenuating influenza A (H5N1) virus–associated acute lung injury

H Loy, DIT Kuok, KPY Hui, MHL Choi… - The Journal of …, 2019 - academic.oup.com
Background Highly pathogenic avian influenza viruses can cause severe forms of acute
lung injury (ALI) in humans, where pulmonary flooding leads to respiratory failure. The …

Efficacy and Safety of Mesenchymal Stem Cell Transplantation in the Treatment of Autoimmune Diseases (Rheumatoid Arthritis, Systemic Lupus Erythematosus …

L Zeng, G Yu, K Yang, W Xiang, J Li… - Stem cells …, 2022 - Wiley Online Library
Objective. To evaluate the efficacy and safety of mesenchymal stem cell (MSC)
transplantation in the treatment of autoimmune diseases. Methods. The Chinese and …

Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential

E Gorman, J Millar, D McAuley… - Expert review of …, 2021 - Taylor & Francis
Introduction: Mesenchymal stromal (stem) cell (MSC) therapies are emerging as a promising
therapeutic intervention in patients with Acute Respiratory Distress Syndrome (ARDS) and …

Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds

PS Couto, MC Rotondi, A Bersenev, CJ Hewitt… - Biotechnology …, 2020 - Elsevier
Human mesenchymal stem/stromal cells (hMSCs) present a key therapeutic cellular
intervention for use in cell and gene therapy (CGT) applications due to their …

Regulatory perspective on in vitro potency assays for human mesenchymal stromal cells used in immunotherapy

C De Wolf, M Van De Bovenkamp, M Hoefnagel - Cytotherapy, 2017 - Elsevier
Mesenchymal stromal cells (MSCs) are multipotent cells derived from various tissues that
can differentiate into several cell types. MSCs are able to modulate the response of immune …

The secretome derived from 3D-cultured umbilical cord tissue MSCs counteracts manifestations typifying rheumatoid arthritis

JP Miranda, SP Camões, MM Gaspar… - Frontiers in …, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disorder whose treatment is mostly restricted to
pain and symptom management and to the delay of joint destruction. Mesenchymal …

Cell membrane-based biomimetic nanosystems for advanced drug delivery in cancer therapy: A comprehensive review

J Zhao, J Ruan, G Lv, Q Shan, Z Fan, H Wang… - Colloids and Surfaces B …, 2022 - Elsevier
Natural types of cells display distinct characteristics with homotypic targeting and extended
circulation in the blood, which are worthy of being explored as promising drug delivery …

Exosomes derived from human umbilical cord mesenchymal stem cells alleviate Parkinson's disease and neuronal damage through inhibition of microglia

ZX Zhang, YJ Zhou, P Gu, W Zhao… - Neural Regeneration …, 2023 - journals.lww.com
Microglia-mediated inflammatory responses have been shown to play a crucial role in
Parkinson's disease. In addition, exosomes derived from mesenchymal stem cells have …