The free radical nitric oxide (· NO) is a key mediator in different physiological processes such
as vasodilation, neurotransmission, inflammation, and cellular immune responses, and thus …

The control of neuropathic pain is a leading challenge in modern medicine. Traditional
medicine has, for a long time, used natural compounds such as nutraceuticals for this …

Chronic pain has attracted wide interest because it is a major obstacle affecting the quality of
life. Consequently, safe, efficient, and low‐addictive drugs are highly desirable …

Osteoarthritis (OA) is a disease caused by joint degeneration with massive cartilage loss,
and obesity is among the risk factors for its onset, though the pathophysiological …

Infants admitted to neonatal intensive care units are repeatedly stimulated by painful events,
especially if intubated. Preterm infants are known to have greater pain perception than full …

The present study aimed to investigate the cardioprotective role of berberine in sepsis‑
induced cardiac dysfunction and consider the underlying mechanisms. C57BL/6J mice were …

Over the last decade, the convergence of advanced materials and innovative applications
has fostered notable scientific progress within the biomedical and pharmaceutical fields …

This work aimed to obtain and characterize anthocyanin-rich extracts (ARE) from native
black beans and evaluate their antioxidant and anti-inflammatory potential. The initial extract …

Peroxynitrite, a short-lived and reactive oxidant, emerges from the diffusion-controlled
reaction between the superoxide radical and nitric oxide. Evidence shows that peroxynitrite …

Paclitaxel is a chemotherapeutic drug used for cancer treatment. Chemotherapy-induced
peripheral neuropathy (CIPN) is a common major dose-limiting side effect of many …