The function of articular cartilage depends on its structure and composition, sensitively
impaired in disease (eg osteoarthritis, OA). Responses of chondrocytes to tissue loading are …

Background Repair procedures and tissue engineering are solutions available in the clinical
practice for the treatment of damaged articular cartilage. Regulatory bodies defined the …

Objective During exercise, cartilage recovers interstitial fluid lost during inactivity, which
explains how tissue thickness and joint space are maintained over time. This recovery …

Articular cartilage is known to be anisotropic and inhomogeneous because of its
microstructure. In particular, its elastic properties are influenced by the arrangement of the …

The extent to which articular cartilage hydraulic permeability is anisotropic is largely
unknown, despite its importance for understanding mechanisms of joint lubrication, load …

With the aim of providing information for modelling joint and limb systems, widely available
constitutive hyperelastic laws are evaluated in this paper for their ability to predict the …

Recent imaging has revealed that in vivo contact deformations of human knee cartilage
under physiological loadings are surprisingly large—typically on the order of 10%, but up to …

The mechanics of cartilage injuries have implications for repair strategies. We examined the
role of strain rate in cartilage injury under compression near the “gel diffusion” rate (the …

We now want to begin to develop a holistic view of cartilage as a tissue that has an
integrated set of homeostatic processes for maintaining itself. In the context of other tissues …

Loading-induced cartilage exudation causes loss of fluid from the tissue, joint space thinning
and, in a long term prospective, the insurgence of osteoarthritis. Fortunately, experiments …