Biosynthesis and function of modified bases in bacteria and their viruses

P Weigele, EA Raleigh - Chemical reviews, 2016 - ACS Publications
Naturally occurring modification of the canonical A, G, C, and T bases can be found in the
DNA of cellular organisms and viruses from all domains of life. Bacterial viruses …

DNA methyltransferases: from evolution to clinical applications

VM Del Castillo Falconi, K Torres-Arciga… - International journal of …, 2022 - mdpi.com
DNA methylation is an epigenetic mark that living beings have used in different
environments. The MTases family catalyzes DNA methylation. This process is conserved …

Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131

NL Ben Zakour, AS Alsheikh-Hussain, MM Ashcroft… - MBio, 2016 - Am Soc Microbiol
Escherichia coli ST131 is the most frequently isolated fluoroquinolone-resistant (FQR) E. coli
clone worldwide and a major cause of urinary tract and bloodstream infections. Although …

Conserved DNA methyltransferases: a window into fundamental mechanisms of epigenetic regulation in bacteria

PH Oliveira, G Fang - Trends in microbiology, 2021 - cell.com
An increasing number of studies have reported that bacterial DNA methylation has important
functions beyond the roles in restriction-modification systems, including the ability of …

Identification of IncA/C plasmid replication and maintenance genes and development of a plasmid multilocus sequence typing scheme

SJ Hancock, MD Phan, KM Peters… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Plasmids of incompatibility group A/C (IncA/C) are becoming increasingly prevalent within
pathogenic Enterobacteriaceae. They are associated with the dissemination of multiple …

Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic Escherichia coli (ExPEC) …

S Shaik, A Ranjan, SK Tiwari, A Hussain… - MBio, 2017 - Am Soc Microbiol
Escherichia coli sequence type 131 (ST131), a pandemic clone responsible for the high
incidence of extraintestinal pathogenic E. coli (ExPEC) infections, has been known widely …

Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant Staphylococcus aureus

R Copin, WE Sause, Y Fulmer… - Proceedings of the …, 2019 - National Acad Sciences
The past two decades have witnessed an alarming expansion of staphylococcal disease
caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) …

Phasevarions of bacterial pathogens: methylomics sheds new light on old enemies

JM Atack, A Tan, LO Bakaletz, MP Jennings… - Trends in microbiology, 2018 - cell.com
A wide variety of bacterial pathogens express phase-variable DNA methyltransferases that
control expression of multiple genes via epigenetic mechanisms. These randomly switching …

Phasevarions of bacterial pathogens–phase-variable epigenetic regulators evolving from restriction–modification systems

ZN Phillips, AU Husna, MP Jennings… - …, 2019 - microbiologyresearch.org
Phase-variable DNA methyltransferases control the expression of multiple genes via
epigenetic mechanisms in a wide variety of bacterial species. These systems are called …

“Omics” Technologies - What Have They Told Us About Uropathogenic Escherichia coli Fitness and Virulence During Urinary Tract Infection?

S Torres-Puig, V García, K Stærk… - Frontiers in cellular …, 2022 - frontiersin.org
Uropathogenic Escherichia coli (UPEC) is the main etiological agent of urinary tract infection
(UTI), a widespread infectious disease of great impact on human health. This is further …