Eg5, the product of Kif11 gene, also known as kinesin spindle protein, is a motor protein
involved in the proper establishment of a bipolar mitotic spindle. Eg5 is one of the 45 …

Motor proteins include several protein families (Kinesin, Dynein and Myosin) responsible for
intracellular transport, intercellular communication, among other functions. In cancer cells …

The proliferative and invasive nature of malignant cancers drives lethality. In glioblastoma,
these two processes are presumed mutually exclusive and hence termed “go or grow.” We …

Purpose The study aimed to search and identify genes that were differentially expressed in
breast cancer, and their roles in cancer growth and progression. Materials and Methods The …

A simple and novel methodology has been developed for the synthesis of 1, 3-bis
(carboxymethyl) imidazolium chloride [BCMIM][Cl] salt. The ionic salt [BCMIM][Cl] catalyzed …

Kinesin motor proteins exert essential cellular functions in all eukaryotes. They control
mitosis, migration and intracellular transport through interaction with microtubules. Small …

Background Lung adenocarcinoma (LUAD) is challenging in clinical practice due to the poor
understanding of molecular mechanisms and limited therapeutic targets. Herein, the work …

Novel pyrimidinic selenoureas were synthesized and evaluated against tumour and normal
cell lines. Among these, the compound named 3j initially showed relevant cytotoxicity and …

Objectives Diabetic retinopathy (DR) is a severe complication of chronic diabetes. The
C1q/TNF-related protein family (CTRPs) has been demonstrated to exert protective effects …

Aims Kinesin family member 11 (Kif11) is a member of the kinesin family motor proteins,
which is associated with spindle formation and tumour genesis. In this study, we investigated …