Microbial production of advanced biofuels

J Keasling, H Garcia Martin, TS Lee… - Nature Reviews …, 2021 - nature.com
Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …

Structural and chemical biology of terpenoid cyclases

DW Christianson - Chemical reviews, 2017 - ACS Publications
The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

Origin and early evolution of the plant terpene synthase family

Q Jia, R Brown, TG Köllner, J Fu… - Proceedings of the …, 2022 - National Acad Sciences
As a midsized gene family conserved more by lineage than function, the typical plant
terpene synthases (TPSs) could be a valuable tool to examine plant evolution. TPSs are …

Decoding catalysis by terpene synthases

JN Whitehead, NGH Leferink, LO Johannissen… - ACS …, 2023 - ACS Publications
The review by Christianson, published in 2017 on the twentieth anniversary of the
emergence of the field, summarizes the foundational discoveries and key advances in …

Terpenes and isoprenoids: a wealth of compounds for global use

SD Tetali - Planta, 2019 - Springer
Main conclusion Role of terpenes and isoprenoids has been pivotal in the survival and
evolution of higher plants in various ecoregions. These products find application in the …

[HTML][HTML] Terpene synthases as metabolic gatekeepers in the evolution of plant terpenoid chemical diversity

PS Karunanithi, P Zerbe - Frontiers in plant science, 2019 - frontiersin.org
Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

PJ Rutledge, GL Challis - Nature reviews microbiology, 2015 - nature.com
Microorganisms produce a wealth of structurally diverse specialized metabolites with a
remarkable range of biological activities and a wide variety of applications in medicine and …

Biosynthesis and biological functions of terpenoids in plants

D Tholl - Biotechnology of isoprenoids, 2015 - Springer
<? xm-replace_text {Heading}?> Abstract Terpenoids (isoprenoids) represent the largest
and most diverse class of chemicals among the myriad compounds produced by plants …

Euphorbia diterpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)

Z Zhan, S Li, W Chu, S Yin - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 2013 to 2021 As the characteristic metabolites of Euphorbia plants, Euphorbia
diterpenoids have always been a hot topic in related science communities due to their …

[HTML][HTML] Cytochrome P450 enzymes: a driving force of plant diterpene diversity

U Bathe, A Tissier - Phytochemistry, 2019 - Elsevier
In plant terpene biosynthesis, oxidation of the hydrocarbon backbone produced by terpene
synthases is typically carried out by cytochrome P450 oxygenases (CYPs). The …