Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms of action

JR Ussher, DJ Drucker - Nature Reviews Cardiology, 2023 - nature.com
Type 2 diabetes mellitus (T2DM) and obesity are metabolic disorders characterized by
excess cardiovascular risk. Glucagon-like peptide 1 (GLP1) receptor (GLP1R) agonists …

Doppler echocardiography assessment of coronary microvascular function in patients with angina and no obstructive coronary artery disease

J Schroder, E Prescott - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Echocardiographic evaluation is an essential part of the diagnostic work-up in patients with
known or suspected cardiovascular disease. Transthoracic Doppler echocardiography …

Efficacy of liraglutide in obesity in children and adolescents: systematic review and meta-analysis of randomized controlled trials

A Cornejo-Estrada, C Nieto-Rodriguez… - Children, 2023 - mdpi.com
In the past few decades, childhood obesity has become a significant global health issue,
impacting around 107.7 million children and adolescents globally. There is currently minimal …

Medical treatment of weight loss in children and adolescents with obesity

V Calcaterra, V Rossi, A Mari, F Casini… - Pharmacological …, 2022 - Elsevier
Obesity remains one of the biggest health problems both in adults and children. Lifestyle
modification, including diet and exercise, continues to be the mainstay of obesity prevention …

Efficacy of liraglutide in non-diabetic obese adults: a systematic review and meta-analysis of randomized controlled trials

JJ Barboza, MR Huaman, B Melgar… - Journal of Clinical …, 2022 - mdpi.com
Objective: We systematically assessed the efficacy of liraglutide in non-diabetic obese
adults. Methods: Six databases were searched up to July 2021 for randomized controlled …

Microvascular dysfunction in obesity-hypertension

T Do, A Van, A Ataei, S Sharma… - Current Hypertension …, 2023 - Springer
Abstract Purpose of Review This review aims to explore the role of microvascular
dysfunction in obesity-hypertension, discuss the effects obesity has on renal …

GLP-1 receptor agonists and coronary arteries: from mechanisms to events

A Pahud de Mortanges, E Sinaci… - Frontiers in …, 2022 - frontiersin.org
Objective: Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) lower plasma glucose
through effects on insulin and glucagon secretion and by decelerating gastric emptying. GLP …

Comprehensive treatment of microvascular angina in overweight women–a randomized controlled pilot trial

KB Bove, M Nilsson, LR Pedersen, N Mikkelsen… - PLoS …, 2020 - journals.plos.org
Aims Coronary microvascular dysfunction (CMD) carries a poor cardiovascular prognosis
and may explain angina in women without obstructive coronary artery disease (CAD) …

New Insights into the Use of Liraglutide—Impact on Cardiovascular Risk and Microvascular Outcomes

M Wronka, J Krzemińska, E Młynarska, J Rysz… - Biomedicines, 2023 - mdpi.com
Despite the availability of many glucose-lowering drugs, patients with type 2 diabetes
mellitus (T2DM) often do not achieve the desired effect, and cardiovascular complications …

The role of coronary microcirculation in heart failure with preserved ejection fraction: An unceasing odyssey

K Dimitriadis, P Theofilis, G Koutsopoulos… - Heart Failure …, 2024 - Springer
Heart failure with preserved ejection fraction (HFpEF) represents an entity with complex
pathophysiologic pathways, among which coronary microvascular dysfunction (CMD) is …