A unique organelle for studying membrane biochemistry is the mitochondrion whose
functionality depends on a coordinated supply of proteins and lipids. Mitochondria are …

Lipases and phospholipases are interfacial enzymes that hydrolyze hydrophobic ester
linkages of triacylglycerols and phospholipids, respectively. In addition to their role as …

Phosphatidic acid (PA) is a critical phospholipid constituent in eukaryotic cell membranes,
which accounts for 1À4% of the total lipid. 1 This lipophilic glycerophospholipid has a …

COPII vesicle formation requires only three coat assembly subunits: Sar1p, Sec13/31p, and
Sec23/24p. PI 4-phosphate or PI 4, 5-bisphosphate is required for the binding of these …

Phospholipids are emerging as novel second messengers in plant cells. They are rapidly
formed in response to a variety of stimuli via the activation of lipid kinases or …

Interaction of extracellular-signal molecules with cell-surface receptors often activates a
phospholipase D (PLD)-mediated hydrolysis of phosphatidylcholine and other …

1.1. Background Beginning in the early 1980s, cell biologists started realising that some
phospholipids are not just basic constituents of membranes but dynamic informational …

La phospholipase D catalyse l'hydrolyse de la liaison phosphodiester des
glycérophospholipides, ce qui produit l'acide phosphatidique et un alcool polaire. Des …

This review focuses on two phospholipase activities involved in eukaryotic signal
transduction. The action of the phosphatidylinositol-specific phospholipase C enzymes …

Glycerophospholipids are the most abundant membrane lipid constituents in most
eukaryotic cells. As a consequence, phospholipid class and acyl chain homeostasis are …