Synthesis, spectroscopic characterization, reactive properties by DFT calculations, molecular dynamics simulations and biological evaluation of Schiff bases tethered …

RR Pillai, K Karrouchi, S Fettach, S Armaković… - Journal of Molecular …, 2019 - Elsevier
The synthesis, spectroscopic characterization, reactivity study and evaluation of antioxidant
and α-glucosidase inhibitory activities of two Schiff bases containing 1, 2, 4-triazole and …

Synthesis, antioxidant activity, docking simulation, and computational investigation of novel heterocyclic compounds and Schiff bases from picric acid

H Bayrak, AM Fahim, FY Karahalil, I Azafad… - Journal of Molecular …, 2023 - Elsevier
In this elucidation, we used the available picric acid commercial for the synthesis of different
heterocyclics such as carbothioamide and 1, 3, 4-oxadiazole and different Schiff bases …

Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold

R Aggarwal, M Hooda, P Kumar, G Sumran - Topics in Current Chemistry, 2022 - Springer
The present review article strives to compile the latest synthetic approaches for the synthesis
of triazolothiadiazine and its derivatives, along with their diverse pharmacological activities …

[HTML][HTML] Synthetic Methods and Pharmacological Potentials of Triazolothiadiazines: A Review

MS Mostafa, IAM Radini, NMA El-Rahman, RE Khidre - Molecules, 2024 - mdpi.com
This review article examines the synthetic pathways for triazolothiadiazine derivatives, such
as triazolo [3, 4-b] thiadiazines, triazolo [5, 1-b] thiadiazines, and triazolo [4, 3-c] …

Design, synthesis and evaluation of novel 1, 2, 4-triazole derivatives as promising anticancer agents

L Emami, S Sadeghian, A Mojaddami, S Khabnadideh… - BMC chemistry, 2022 - Springer
Herein, we reported the synthesis of nineteen novel 1, 2, 4-triazole derivatives including 1, 3-
diphenyl-2-(1H-1, 2, 4-triazol-1-yl) propan-1-ones (7a-e), 1-(1, 3-diphenylpropan-2-yl)-1 H-1 …

Synthesis, Solvent effects, Chemical reactivity, Molecular Docking and Molecular Dynamic Studies of Triazole derivative

G Venkatesh, Y Sixto-López, P Vennila, V Siva… - Journal of Molecular …, 2024 - Elsevier
In the present study,(E)-3-(2-(4-amino-5-mercapto-4H-1, 2, 4-triazol-3-yl) hydrazono) methyl)-
2-bromo-6-methoxyphenol (AMTMP) is synthesized and characterized utilizing FT-IR, FT …

Synthesis, Characterization, Free-radical Scavenging Capacity and Antioxidant Activity of Novel Series of Hydrazone, 1, 3, 4-oxadiazole and 1, 2, 4-triazole Derived …

K Karrouchi, S Fettach, S Radi, E Yousfi… - Letters in Drug …, 2019 - benthamdirect.com
Background: Pyrazole is an important class of heterocyclic compound, has been shown to
exhibit diverse biological and pharmacological activities such as anti-inflammatory, anti …

Effect of precursor pH on structural, magnetic and catalytic properties of CoFe2O4@SiO2 green nanocatalyst

PP Bardapurkar, SS Shewale, SA Arote… - Research on Chemical …, 2021 - Springer
Cobalt ferrite is a promising material for many therapeutic applications, photo-catalysis, gas
detectors, high-density data storage, etc. Optimization of process parameters has a vital role …

Radiation-synthesis of chitosan/poly (acrylic acid) nanogel for improving the antitumor potential of rutin in hepatocellular carcinoma

RR Radwan, HE Ali - Drug Delivery and Translational Research, 2021 - Springer
The current study aimed to investigate the ability of chitosan/poly (acrylic acid) nanogel
(CAN) to improve the bioavailability and anticancer potential of rutin. Synthesis of CAN was …

Probing N-substituted 4-(5-mercapto-4-ethyl-4H-1, 2, 4-triazol-3-yl)-N-phenylpiperdine-1-carboxamides as potent 15-LOX inhibitors supported with ADME, DFT …

Z Nawaz, N Riaz, M Saleem, A Iqbal, SA Ejaz… - Heliyon, 2024 - cell.com
In our continuous efforts to find out leads against the enzyme 15-lipoxygenase (15-LOX), the
current study deals with the synthesis of a series of new N-alkyl/aralkyl/aryl derivatives of 2 …