Immune-related adverse events of checkpoint inhibitors

M Ramos-Casals, JR Brahmer, MK Callahan… - Nature reviews Disease …, 2020 - nature.com
Cancer immunotherapies have changed the landscape of cancer treatment during the past
few decades. Among them, immune checkpoint inhibitors, which target PD-1, PD-L1 and …

Clinical and translational attributes of immune-related adverse events

KPM Suijkerbuijk, MJM van Eijs, F van Wijk… - Nature Cancer, 2024 - nature.com
With immune checkpoint inhibitors (ICIs) becoming the mainstay of treatment for many
cancers, managing their immune-related adverse events (irAEs) has become an important …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) consensus definitions for immune checkpoint inhibitor-associated immune-related adverse events (irAEs) …

J Naidoo, C Murphy, MB Atkins… - … for immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Immune-related adverse events (irAEs) associated with immune checkpoint inhibitor (ICI)
therapy may vary substantially in their clinical presentation, including natural history …

Epidemiology and risk factors for the development of cutaneous toxicities in patients treated with immune-checkpoint inhibitors: a United States population-level …

S Wongvibulsin, V Pahalyants, M Kalinich… - Journal of the American …, 2022 - Elsevier
Background A variety of dermatoses have been reported in the growing number of patients
treated with immune-checkpoint inhibitors (ICIs), but the current understanding of cutaneous …

Association between immune-related adverse event timing and treatment outcomes

D Hsiehchen, AR Naqash, M Espinoza… - …, 2022 - Taylor & Francis
The timing of immune-related adverse events (irAE) associated with immune checkpoint
inhibitors (ICI) is highly variable. Although the development of irAE has been associated with …

Emerging management approach for the adverse events of immunotherapy of cancer

MM Rahman, T Behl, MR Islam, MN Alam, MM Islam… - Molecules, 2022 - mdpi.com
Immunotherapy, which stimulates the body's immune system, has received a considerable
amount of press in recent years because of its powerful benefits. Cancer immunotherapy …

[HTML][HTML] Prediction of severe immune-related adverse events requiring hospital admission in patients on immune checkpoint inhibitors: study of a population level …

M Kalinich, W Murphy, S Wongvibulsin… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Immune-related adverse events (irAEs) are a serious side effect of immune
checkpoint inhibitor (ICI) therapy for patients with advanced cancer. Currently, predisposing …

Molecular correlates of response to eribulin and pembrolizumab in hormone receptor-positive metastatic breast cancer

TE Keenan, JL Guerriero, R Barroso-Sousa, T Li… - Nature …, 2021 - nature.com
Immune checkpoint inhibitors (ICIs) have minimal therapeutic effect in hormone receptor-
positive (HR+) breast cancer. We present final overall survival (OS) results (n= 88) from a …

Advances in knowledge and management of immune-related adverse events in cancer immunotherapy

TA Olsen, TZ Zhuang, S Caulfield, DJ Martini… - Frontiers in …, 2022 - frontiersin.org
Immune-oncologic (IO) therapy has revolutionized the treatment and management of
oncologic disease. Immunotherapy functions by enhancing the host immune-systems ability …

Immunotherapy in hepatocellular carcinoma: evaluation and management of adverse events associated with atezolizumab plus bevacizumab

C Hsu, L Rimassa, HC Sun, A Vogel… - … Advances in Medical …, 2021 - journals.sagepub.com
In light of positive efficacy and safety findings from the IMbrave150 trial of atezolizumab plus
bevacizumab, this novel combination has become the preferred first-line standard of care for …