The first therapeutic nucleic acid, a DNA oligonucleotide, was approved for clinical use in
1998. Twenty years later, in 2018, the first therapeutic RNA-based oligonucleotide was …

Purpose The present review aimed to assess the role of exosomal miRNAs in cancer-
associated fibroblasts (CAFs), normal fibroblasts (NFs), and cancer cells. The roles of …

Background: IsomiR is an isoform of microRNA (miRNA), and its sequences vary from those
of a reference miRNA, which arose with the advencements of deep sequencing, high miRNA …

Cardiovascular disease (CVD) remains the predominant cause of human morbidity and
mortality in developed countries. Currently, microRNAs have been investigated in many …

Cardiovascular diseases (CVDs) encompass a range of disorders, from congenital heart
malformation, cardiac valve, peripheral artery, coronary artery, cardiac muscle diseases, and …

Radiotherapy is widely used in the clinical treatment of cancer patients and it may be used
alone or in combination with surgery or chemotherapy to inhibit tumor development …

MicroRNAs (miRNAs) are a class of noncoding RNAs of about 19–25 nucleotides, which
serve as critical modulators of various cellular and biological processes by target gene …

Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related death
with a limited efficacy of treatment for intermediate and advanced stages of the disease …

p53 is known as the guardian of the genome and plays various roles in DNA damage and
cancer suppression. The p53 gene was found to express multiple p53 splice variants …

Abstract Background Circulating microRNAs (miRNAs) are considered a hot spot of
research that can be employed for monitoring and/or diagnostic purposes in coronary artery …