[HTML][HTML] Evolution of the human pathogenic lifestyle in fungi

A Rokas - Nature Microbiology, 2022 - nature.com
Fungal pathogens cause more than a billion human infections every year, resulting in more
than 1.6 million deaths annually. Understanding the natural history and evolutionary ecology …

[HTML][HTML] Treatment strategies for cryptococcal infection: challenges, advances and future outlook

KR Iyer, NM Revie, C Fu, N Robbins… - Nature Reviews …, 2021 - nature.com
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Toward a fully resolved fungal tree of life

TY James, JE Stajich, CT Hittinger… - Annual Review of …, 2020 - annualreviews.org
In this review, we discuss the current status and future challenges for fully elucidating the
fungal tree of life. In the last 15 years, advances in genomic technologies have …

[HTML][HTML] Notes, outline and divergence times of Basidiomycota

MQ He, RL Zhao, KD Hyde, D Begerow, M Kemler… - Fungal diversity, 2019 - Springer
The Basidiomycota constitutes a major phylum of the kingdom Fungi and is second in
species numbers to the Ascomycota. The present work provides an overview of all validly …

Fungal nomenclature: managing change is the name of the game

SE Kidd, A Abdolrasouli, F Hagen - Open forum infectious …, 2023 - academic.oup.com
Fungal species have undergone and continue to undergo significant nomenclatural change,
primarily due to the abandonment of dual species nomenclature in 2013 and the …

Fungal species concepts in the genomics era

J Xu - Genome, 2020 - cdnsciencepub.com
The 140 000 or so fungal species reported so far are heterogeneously defined based on
varying criteria such as morphological, physiological, mating, and (or) molecular features …

[HTML][HTML] 5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus

RB Billmyre, S Applen Clancey, LX Li… - Nature …, 2020 - nature.com
Patients infected with the fungal pathogen Cryptococcus are most effectively treated with a
combination of 5-fluorocytosine (5FC) and amphotericin B. 5FC acts as a prodrug, which is …

A new lineage of Cryptococcus gattii (VGV) discovered in the Central Zambezian Miombo Woodlands

RA Farrer, M Chang, MJ Davis, L van Dorp, DH Yang… - MBio, 2019 - Am Soc Microbiol
We discovered a new lineage of the globally important fungal pathogen Cryptococcus gattii
on the basis of analysis of six isolates collected from three locations spanning the Central …

[HTML][HTML] The evolving species concepts used for yeasts: from phenotypes and genomes to speciation networks

T Boekhout, MC Aime, D Begerow, T Gabaldón… - Fungal diversity, 2021 - Springer
Here we review how evolving species concepts have been applied to understand yeast
diversity. Initially, a phenotypic species concept was utilized taking into consideration …

[HTML][HTML] What's New in Cryptococcus gattii: From Bench to Bedside and Beyond

J Beardsley, A Dao, C Keighley, K Garnham… - Journal of Fungi, 2022 - mdpi.com
Cryptococcus species are a major cause of life-threatening infections in
immunocompromised and immunocompetent hosts. While most disease is caused by …