A diverse spectrum of vanadium compounds have arisen, over the past years, as potential
therapeutic agents for the treatment of malignancies. Poised to delineate the role of that …

The zebrafish (Danio rerio) is now the pre-eminent vertebrate model system for clarification
of the roles of specific genes and signaling pathways in development. The zebrafish …

Zebrafish is recognized as one of the most important vertebrate model organisms; however,
its value in pharmacological studies has not been extensively explored and exploited. In this …

Cancer is a group of diseases involving abnormal cell growth. The cells grow uncontrollably
with the potential to invade and spread to other parts of the body. This disease is one of the …

The purpose of this paper is to summarize mode of action of cisplatin on the tumor cells, a
brief outlook on the metallocene compounds as antitumor drugs as well as the future …

Vanadium compounds have been known to have beneficial therapeutic properties since the
turn of the century, but it was not until 1965 when it was discovered that those effects could …

Phosphotyrosine signaling is regulated by the opposing actions of protein tyrosine kinases
(PTKs) and protein tyrosine phosphatases (PTPs). Here we discuss the potential of …

Metal complexes are widely employed in cancer treatment. The several tuning variables
provide peerless possibilities for drug development strategies. This results in a diverse …

Among the 25 bis (cyclopentadienyl) vanadium (IV) and 14 oxovanadium (IV) compounds
synthesised and evaluated for anticancer activity, bis (4, 7-dimethyl-1, 10-phenanthroline) …

Abstract Hexavalent chromium [Cr (VI)] compounds are established human lung
carcinogens. The carcinogenicity of Cr (VI) is related to its solubility, with the most potent …